Evidence map›Paper›PMID 38060634›Full record

ArticleScience (New York, N.Y.)2023

Self-enhancing sono-inks enable deep-penetration acoustic volumetric printing.

Xiao Kuang, Qiangzhou Rong, Saud Belal, Tri Vu, Alice M López López, Nanchao Wang, Mehmet Onur Arıcan, Carlos Ezio Garciamendez-Mijares, Maomao Chen, Junjie Yao and 1 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Cryopreservative Bioink Enables Direct Bioprinting of Adherent Cells.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  7. Review
  8. Article
  9. Tissue-bioelectronics interfaces.Chemical Society reviews · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  17. Article
  18. Review
  19. Review
  20. The 2026 guided acoustic waves roadmap.Journal of physics D: Applied physics · 2026
    Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiao Kuang *Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA.ORCID 0000-0001-6596-1417
Qiangzhou Rong *Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.ORCID 0000-0002-7549-9278
Saud Belal *Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Tri VuDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Alice M López LópezDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA.
Nanchao WangDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.ORCID 0000-0002-5037-4145
Mehmet Onur ArıcanDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA.ORCID 0000-0003-3776-9174
Carlos Ezio Garciamendez-MijaresDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA.ORCID 0000-0003-2433-9773
Maomao ChenDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.ORCID 0000-0003-3692-1138
Junjie YaoDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.ORCID 0000-0002-2381-706X
Yu Shrike ZhangDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA.ORCID 0000-0002-0045-0808

Funding

High-resolution High-speed Photoacoustic and Ultrasound Imaging of SmallVessel Functions in Ischemic StrokeR01NS111039 · NINDS · DUKE UNIVERSITY · PI YAO, JUNJIE · 2019 to 2023
$2.7M
High-throughput Imaging-integrated Vascular Model for Understanding Thromboembolism and Therapeutics ScreeningR01HL166522 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Junjie Yao, Y. Shrike Zhang · 2023 to 2026
$2.7M
Biomaterials for embolization and ablation of arterio-venous malformationsR01HL165176 · NHLBI · MAYO CLINIC ARIZONA · PI OKLU, RAHMI, ZHANG, Y. SHRIKE · 2022 to 2025
$2.6M
Stretchable Hydrogel Bioinks-Enabled Microfluidic Bioprinting of Functional Small-Diameter Blood VesselsR01HL153857 · NHLBI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ZHAO, XUANHE · 2020 to 2024
$2.4M
Head-mounted Photoacoustic Imaging of Deep-brain Neural Activities in Freely Behaving AnimalsRF1NS115581 · NINDS · DUKE UNIVERSITY · PI VERKHUSHA, VLADISLAV, YAO, JUNJIE · 2020 to 2020
$2.0M
High-Throughput Volumetric Photoacoustic Imaging of Living Vascularized OrganoidsR01EB028143 · NIBIB · DUKE UNIVERSITY · PI YAO, JUNJIE · 2019 to 2022
$2.0M
A Bioprinted Volumetric Model of Vascularized GlioblastomaR01CA282451 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI Kaisorn Lee Chaichana, Y. Shrike Zhang · 2023 to 2026
$1.7M
3D Functional Photoacoustic Imaging of Human Brain with a Stretchable Ultrasound Matrix ArrayR01EB031629 · NIBIB · PENNSYLVANIA STATE UNIVERSITY, THE · PI JING, YUN · 2021 to 2022
$955k
Multiscale Stereolithogrphic Bioprinting of Stage-Matching Vascularized Tumor ModelsR21EB025270 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI ZHANG, Y. SHRIKE · 2018 to 2020
$726k
Transcranial Photoacoustic Imaging Using a Virtual ArrayR21EB027981 · NIBIB · PENNSYLVANIA STATE UNIVERSITY, THE · PI JING, YUN · 2020 to 2020
$455k
Photoacoustic-imaging-guided intravascular sonothrombolysisR21EB027304 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI JIANG, XIAONING, YAO, JUNJIE · 2019 to 2020
$411k
NCI NIH HHS R01 CA282451NHLBI NIH HHS R01 HL153857NHLBI NIH HHS R01 HL165176NHLBI NIH HHS R01 HL166522NIBIB NIH HHS R01 EB028143NIBIB NIH HHS R01 EB031629NIBIB NIH HHS R21 EB025270NIBIB NIH HHS R21 EB027304NIBIB NIH HHS R21 EB027981NINDS NIH HHS R01 NS111039NINDS NIH HHS RF1 NS115581
6 · The paper itself

Abstract

Volumetric printing, an emerging additive manufacturing technique, builds objects with enhanced printing speed and surface quality by forgoing the stepwise ink-renewal step. Existing volumetric printing techniques almost exclusively rely on light energy to trigger photopolymerization in transparent inks, limiting material choices and build sizes. We report a self-enhancing sonicated ink (or sono-ink) design and corresponding focused-ultrasound writing technique for deep-penetration acoustic volumetric printing (DAVP). We used experiments and acoustic modeling to study the frequency and scanning rate-dependent acoustic printing behaviors. DAVP achieves the key features of low acoustic streaming, rapid sonothermal polymerization, and large printing depth, enabling the printing of volumetric hydrogels and nanocomposites with various shapes regardless of their optical properties. DAVP also allows printing at centimeter depths through biological tissues, paving the way toward minimally invasive medicine.

Identifiers

PMID38060634
PMCPMC11034850

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.