Evidence map›Paper›PMID 38060593›Full record

ArticlePLoS neglected tropical diseases2023

Phylogeographic characterization of Burkholderia pseudomallei isolated from Bangladesh.

Md Shariful Alam Jilani, Saika Farook, Arittra Bhattacharjee, Lovely Barai, Chowdhury Rafiqul Ahsan, Jalaluddin Ashraful Haq, Apichai Tuanyok

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Md Shariful Alam JilaniDepartment of Microbiology, Ibrahim Medical College, Dhaka, Bangladesh.ORCID 0000-0003-1143-5272
Saika FarookDepartment of Microbiology, Ibrahim Medical College, Dhaka, Bangladesh.
Arittra BhattacharjeeBioinformatics Division, National Institute of Biotechnology, Savar, Dhaka, Bangladesh.
Lovely BaraiDepartment of Microbiology, BIRDEM General Hospital, Dhaka, Bangladesh.
Chowdhury Rafiqul AhsanDepartment of Microbiology, University of Dhaka, Dhaka, Bangladesh.
Jalaluddin Ashraful HaqDepartment of Microbiology, Ibrahim Medical College, Dhaka, Bangladesh.
Apichai TuanyokDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, United States of America.
Ibrahim Cardiac Hospital & Research Institute · BDBangladesh Institute of Research and Rehabilitation for Diabetes Endocrine and Metabolic Disorders · BDNational Institute of BiotechnologyUniversity of Dhaka · BDUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBurkholderia pseudomallei possesses a diverse set of genes which encode a vast array of biological functions reflecting its clinical, ecological and phenotypic diversity. Strain variation is linked to geographic location as well as pattern of land uses. This soil-dwelling Gram-negative pathogen causes melioidosis, a tropical disease endemic in northern Australia and Southeast Asian regions including Bangladesh. Phylogeographic analyses of B. pseudomallei isolates by molecular typing techniques could be used to examine the diversity of this organism as well as to track melioidosis epidemics.

methodsIn this study, 22 B. pseudomallei isolates, of which 20 clinical and two soil isolates were analyzed, utilizing Real-time PCR assay and multilocus sequence typing (MLST). The sequences were then submitted to PubMLST database for analysis and construction of phylogenetic tree.

findingsA total of 12 different sequence types (STs) that includes four novel STs were identified for the first time. Strains having STs 1005, 1007 and 56 were the most widespread STs frequently isolated in Bangladesh. ST 1005, ST 56, ST 1007 and ST 211 have been detected not only in Bangladesh but are also present in many Southeast Asian countries. SIGNIFICANCE: ST 1005 was detected in both soil and clinical samples of Gazipur. Most prevalent, ST 56 has been previously reported from Myanmar, Thailand, Cambodia and Vietnam, confirming the persistence of the genotype over the entire continent. Further large-scale study is necessary to find out the magnitude of the infection and its different reservoirs in the environment along with phylogeographic association.

Indexed as

Burkholderia pseudomalleiMelioidosisBangladeshHumansMultilocus Sequence TypingPhylogenySoilThailandSoil

Identifiers

PMID38060593
PMCPMC10729972
OpenAlexW4389429404

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.