Evidence map›Paper›PMID 38060500›Full record

ArticlePloS one2023

Pharmacy and neighborhood-level variation in cash price of diabetes medications in the United States.

Haider J Warraich, Hasan K Siddiqi, Diane G Li, Jeroen van Meijgaard, Muthiah Vaduganathan

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Haider J WarraichDivision of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.ORCID 0000-0001-9493-1372
Hasan K SiddiqiDivision of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America.
Diane G LiGoodRx Inc, Santa Monica, CA, United States of America.
Jeroen van MeijgaardGoodRx Inc, Santa Monica, CA, United States of America.
Muthiah VaduganathanDivision of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.
Brigham and Women's Hospital · USVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes medications place significant financial burden on patients but less is known about factors affecting cost variation.

objectiveTo examine pharmacy and neighborhood factors associated with cost variation for diabetes drugs in the US. RESEARCH DESIGN, SUBJECTS AND MEASURES: We used all-payer US pharmacy data from 45,874 chain and independent pharmacies reflecting 7,073,909 deidentified claims. We divided diabetes drugs into insulins, non-insulin generic medications, and brand name medications. Generalized linear models, stratified by pharmacy type, identified pharmacy and neighborhood factors associated with higher or lower cash price-per-unit (PPU) for each set of drugs.

resultsCash PPU was highest for brand name therapies ($149.4±203.2), followed by insulins ($42.4±25.0), and generic therapies ($1.3±4.4). Pharmacy-level price variation was greater for non-insulin generic therapies than insulins or brand name therapies. Chain pharmacies had both lower prices and lesser variation compared with independent pharmacies.

conclusionsCash prices for diabetes medications in the US can vary considerably and that the greatest degree of price variation occurs in non-insulin generic therapies.

Indexed as

Diabetes MellitusInsulinsPharmaciesPharmacyDrug CostsDrugs, GenericHumansHypoglycemic AgentsUnited StatesDrugs, GenericHypoglycemic AgentsInsulins

Identifiers

PMID38060500
PMCPMC10703254
OpenAlexW4389455143

What OpenQuestion holds

Textmetadata
LicenceCC0
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.