Evidence map›Paper›PMID 38060461›Full record

ArticlePLOS digital health2023

Implementing a chest X-ray artificial intelligence tool to enhance tuberculosis screening in India: Lessons learned.

Shibu Vijayan, Vaishnavi Jondhale, Tripti Pande, Amera Khan, Miranda Brouwer, Asha Hegde, Ravdeep Gandhi, Venkatesh Roddawar, Shilpa Jichkar, Aniruddha Kadu and 6 more

Abstract read
In one paragraph

Article in PLOS digital health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Shibu VijayanQure.ai, Bangalore, Karnataka, India.ORCID https://orcid.org/0009-0004-6392-622X
Vaishnavi JondhalePATH, Mumbai, India.
Tripti PandeExternal consultant, Washington DC, United States of America.
Amera KhanSTOP TB Partnership, Geneva, Switzerland.
Miranda BrouwerPHTB Consult, 9731 AK. Groningen, The Netherlands.
Asha HegdePATH, Mumbai, India.
Ravdeep GandhiPATH, Mumbai, India.
Venkatesh RoddawarJohn Snow, Inc., New Delhi, Delhi, India.
Shilpa JichkarDepartment of Health Services, Nagpur Municipal Corporation, Nagpur, India.
Aniruddha KaduWorld Health Organization, India.
Sandeep BharaswadkarBill and Melinda Gates Foundation, India.
Mayank SharmaPATH, Mumbai, India.ORCID https://orcid.org/0000-0002-0731-8922
Nathaly Aguilera VasquezMcGill International TB Centre, Montreal, Québec, Canada.
Lucky RichardsonDisha Foundation, Nagpur, India.
Dennis RobertQure.ai, Bangalore, Karnataka, India.ORCID https://orcid.org/0000-0002-8539-6408
Saniya PawarQure.ai, Bangalore, Karnataka, India.

Funding

World Health Organization 001
6 · The paper itself

Abstract

Artificial Intelligence (AI) based chest X-ray (CXR) screening for tuberculosis (TB) is becoming increasingly popular. Still, deploying such AI tools can be challenging due to multiple real-life barriers like software installation, workflow integration, network connectivity constraints, limited human resources available to interpret findings, etc. To understand these challenges, PATH implemented a TB REACH active case-finding program in a resource-limited setting of Nagpur in India, where an AI software device (qXR) intended for TB screening using CXR images was used. Eight private CXR laboratories that fulfilled prerequisites for AI software installation were engaged for this program. Key lessons about operational feasibility and accessibility, along with the strategies adopted to overcome these challenges, were learned during this program. This program also helped to screen 10,481 presumptive TB individuals using informal providers based on clinical history. Among them, 2,303 individuals were flagged as presumptive for TB by a radiologist or by AI based on their CXR interpretation. Approximately 15.8% increase in overall TB yield could be attributed to the presence of AI alone because these additional cases were not deemed presumptive for TB by radiologists, but AI was able to identify them. Successful implementation of AI tools like qXR in resource-limited settings in India will require solving real-life implementation challenges for seamless deployment and workflow integration.

Identifiers

PMID38060461
PMCPMC10703224

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.