ArticleCell reports2023
A mitochondrial inside-out iron-calcium signal reveals drug targets for Parkinson's disease.
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Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
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Who cites it
23 citing papers in PubMed, 25 citations in OpenAlex.
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- Cross-species transcriptomic integration reveals a MIRO1-mediated macrophage-T cell axis in glioma.Life science alliance · 2026Article
- α-Synuclein pathology differentially alters T-type calcium currents in vulnerable and resilient substantia nigra dopaminergic subpopulations.bioRxiv : the preprint server for biology · 2026Article
- Organelle regulation of ferroptosis after intracerebral hemorrhage.Redox biology · 2026Review
- The MIRO1-BAX Complex Dictates Life and Death at the Mitochondrial Gate.bioRxiv : the preprint server for biology · 2026Article
- Dysfunction of the CD38-Miro1 Axis Disrupts Astrocyte-neuron Mitochondrial Transfer in Alzheimer's Disease: Mechanisms and Therapeutic Restoration.Journal of molecular neuroscience : MN · 2026Review
- The iron-energy metabolism axis in Alzheimer's pathogenesis: from mechanisms to interventions.Cell death discovery · 2026Review
- Elevating levels of neuronal MCU in the hippocampus enhances mitochondrial calcium uptake and respiratory efficiency proportional to demand.bioRxiv : the preprint server for biology · 2026Article
- Mitochondrial Calcium Channels and MAM Interaction in Calcium Homeostasis Dysregulation in Parkinson's Disease.Neurochemical research · 2025Review
- Sensing within: Mitochondrial inside-out signal transduction.Cell chemical biology · 2025Review
- Parkinson's disease mutant Miro1 causes mitochondrial dysfunction and dopaminergic neuron loss.Brain : a journal of neurology · 2025Article
- Altered Mitochondrial Bioenergetics and Calcium Kinetics in Young-Onset PLA2G6 Parkinson's Disease iPSCs.Journal of neurochemistry · 2025Article
- Polystyrene Nanoplastics Hitch-Hike the Gut-Brain Axis to Exacerbate Parkinson's Pathology.ACS nano · 2025Article
- The Interplay Between Endoplasmic Reticulum Stress and Ferroptosis in Neurological Diseases.Neurochemical research · 2025Review
- Therapeutic Role of Heterocyclic Compounds in Neurodegenerative Diseases: Insights from Alzheimer's and Parkinson's Diseases.Neurology international · 2025Review
- Article
- Calcium-mediated regulation of mitophagy: implications in neurodegenerative diseases.npj metabolic health and disease · 2025Review
- Pharmacological effects, molecular mechanisms and strategies to improve bioavailability of curcumin in the treatment of neurodegenerative diseases.Frontiers in pharmacology · 2025Review
- Targeting ferroptosis for neuroprotection: potential therapeutic avenues in neurodegenerative and neuropsychiatric diseases.Frontiers in physiology · 2025Review
- Human stem cell-specific epigenetic signatures control transgene expression.Biochimica et biophysica acta. Gene regulatory mechanisms · 2024Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 2 countries.
Vinita BharatDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Aarooran S DurairajDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Roeland VanhauwaertDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Li LiDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Colin M MuirDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Graduate Program of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Sujyoti ChandraDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Chulhwan S KwakDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Yann Le GuenDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA; Institut du Cerveau - Paris Brain Institute - ICM, 75013 Paris, France.
Pawan NandakishoreVroom Inc., Houston, TX 77042, USA.
Chung-Han HsiehDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Stefano E RensiDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Russ B AltmanDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Michael D GreiciusDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.
Liang FengDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Xinnan WangDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: xinnanw@stanford.edu.
Stanford University · USAllen Institute for Brain Science · USStanford Medicine · US
Funding
Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI REIMAN, ERIC MICHAEL · 2001 to 2020
$32.5MNational Brain and Tissue Resource for Parkinson's Disease and Related DisordersU24NS072026 · NINDS · BANNER SUN HEALTH RESEARCH INSTITUTE · PI BEACH, THOMAS G · 2011 to 2015
$7.8MThe Stanford Extreme Phenotypes in Alzheimer's Disease (StEP AD) CohortR01AG060747 · NIA · STANFORD UNIVERSITY · PI GREICIUS, MICHAEL D · 2018 to 2022
$3.4MMolecular Regulations of Mitochondrial Structure in Neuronal Homeostasis and SurvivalR01NS128040 · NINDS · STANFORD UNIVERSITY · PI XINNAN WANG · 2022 to 2026
$2.2MRegulation of mitochondrial motility and mitophagy by LRRK2.R01NS089583 · NINDS · STANFORD UNIVERSITY · PI WANG, XINNAN · 2014 to 2018
$2.0MMolecular Mechanism of Mitochondrial Membrane TransportR01GM138590 · NIGMS · STANFORD UNIVERSITY · PI FENG, LIANG · 2020 to 2023
$1.7MA control center for mitochondrial navigation in neuronsR01GM143258 · NIGMS · STANFORD UNIVERSITY · PI WANG, XINNAN · 2021 to 2024
$1.5MUpgraded High-Content and High-Throughput siRNA Screening SystemS10RR026338 · NCRR · STANFORD UNIVERSITY · PI SOLOW-CORDERO, DAVID EDWARD · 2010 to 2010
$498kNCRR NIH HHS S10 RR026338NIA NIH HHS P30 AG019610NIA NIH HHS R01 AG060747NIGMS NIH HHS R01 GM138590NIGMS NIH HHS R01 GM143258NINDS NIH HHS R01 NS089583NINDS NIH HHS R01 NS128040NINDS NIH HHS U24 NS072026
Abstract
Dysregulated iron or Ca
Indexed as
CalciumParkinson DiseaseHumansIronMitochondriaPharmaceutical PreparationsCalciumIronPharmaceutical PreparationsCP: Neuroscience
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.