Evidence map›Paper›PMID 38060348›Full record

ArticleDiabetes care2024

Ambient Heat and Risk of Serious Hypoglycemia in Older Adults With Diabetes Using Insulin in the U.S. and Taiwan: A Cross-National Case-Crossover Study.

Aayush Visaria, Shu-Ping Huang, Chien-Chou Su, David Robinson, John Read, Chuan-Yao Lin, Rachel Nethery, Kevin Josey, Poonam Gandhi, Benjamin Bates and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Aayush VisariaDepartment of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.ORCID 0000-0002-2170-212X
Shu-Ping HuangChanghua Christian Hospital Institutional Review Board & Administrative Office, Changhua, Taiwan.
Chien-Chou SuInstitute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
David RobinsonDepartment of Geography, Rutgers University, Piscataway, NJ.
John ReadDepartment of Geography, Rutgers University, Piscataway, NJ.
Chuan-Yao LinResearch Center for Environmental Changes, Academia Sinica, Taipei, Taiwan.
Rachel NetheryDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA.
Kevin JoseyDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA.
Poonam GandhiCenter for Pharmacoepidemiology and Treatment Sciences, Rutgers Institute for Health, Health Care Policy, and Aging Research, New Brunswick, NJ.
Benjamin BatesDepartment of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.
Melanie RuaCenter for Pharmacoepidemiology and Treatment Sciences, Rutgers Institute for Health, Health Care Policy, and Aging Research, New Brunswick, NJ.
Ashwagosha ParthasarathiCenter for Pharmacoepidemiology and Treatment Sciences, Rutgers Institute for Health, Health Care Policy, and Aging Research, New Brunswick, NJ.
Arnab K GhoshDepartment of Medicine, Weill Cornell Medical College of Cornell University, New York, NY.
Yea-Huei Kao YangInstitute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.ORCID 0000-0003-4623-5561
Soko SetoguchiDepartment of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.ORCID 0000-0002-1583-752X
Rutgers, The State University of New Jersey · USHarvard University · USChanghua Christian Hospital · TWCornell University · USNational Cheng Kung University · TWNational Cheng Kung University Hospital · TWResearch Center for Environmental Changes, Academia Sinica · TW

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Emily S Barrett · 1988 to 2026
$47.4M
Disease Outcomes iN Older adults under extreme Heat, AiR pollution and Medication use (DO-NO-HARM)R01AG060232 · NIA · RUTGERS, THE STATE UNIV OF N.J. · PI SETOGUCHI IWATA, SOKO · 2019 to 2023
$3.0M
Understanding the long-term effects of hurricanes on cardiovascular health and outcomesK08HL163329 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Arnab Kumar Ghosh · 2023 to 2026
$672k
NHLBI NIH HHS K08 HL163329NIA NIH HHS #1R01AG060232-01A1NIA NIH HHS R01 AG060232NIEHS NIH HHS P30 ES005022
6 · The paper itself

Abstract

objectiveTo measure the association between ambient heat and hypoglycemia-related emergency department visit or hospitalization in insulin users. RESEARCH DESIGN AND

methodsWe identified cases of serious hypoglycemia among adults using insulin aged ≥65 in the U.S. (via Medicare Part A/B/D-eligible beneficiaries) and Taiwan (via National Health Insurance Database) from June to September, 2016-2019. We then estimated odds of hypoglycemia by heat index (HI) percentile categories using conditional logistic regression with a time-stratified case-crossover design.

resultsAmong ∼2 million insulin users in the U.S. (32,461 hypoglycemia case subjects), odds ratios of hypoglycemia for HI >99th, 95-98th, 85-94th, and 75-84th percentiles compared with the 25-74th percentile were 1.38 (95% CI, 1.28-1.48), 1.14 (1.08-1.20), 1.12 (1.08-1.17), and 1.09 (1.04-1.13) respectively. Overall patterns of associations were similar for insulin users in the Taiwan sample (∼283,000 insulin users, 10,162 hypoglycemia case subjects).

conclusionsIn two national samples of older insulin users, higher ambient temperature was associated with increased hypoglycemia risk.

Indexed as

Diabetes MellitusHypoglycemiaAgedCross-Over StudiesHot TemperatureHumansHypoglycemic AgentsInsulinInsulin, Regular, HumanMedicareRetrospective StudiesTaiwanUnited StatesHypoglycemic AgentsInsulinInsulin, Regular, Human

Identifiers

PMID38060348
PMCPMC10834387
OpenAlexW4389455110

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.