SynthesisEnvironmental health perspectives2023
A Nationwide Comparative Analysis of Temperature-Related Mortality and Morbidity in Japan.
Synthesis in Environmental health perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Compound Heatwaves and Health Inequality: A Nationwide Study on Emergency Admissions and Socioeconomic Vulnerability in South Korea.GeoHealth · 2026Article
- Association between ambient temperature and all-cause hospitalization by functional status in Japan: A time-stratified case-crossover study.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Temporal trends in late-pregnancy exposure to ambient temperature and risk of preterm birth in Japan, a nationwide study from 1979 to 2023.The Lancet regional health. Western Pacific · 2026Article
- Determining Location-Specific Thresholds for Heat Warning Systems to Mitigate Heatstroke Mortality in Japan.Environment & health (Washington, D.C.) · 2026Article
- Climate Extremes and Healthcare Access: Assessing the Impact of Severe Weather Events on Emergency Motorcycle Ambulance Availability.Risk management and healthcare policy · 2026Article
- Association of ambient temperature with mortality in community-based patients with severe mental disorders: a time-stratified case-crossover study in western China.BMC psychiatry · 2025Article
- Temperature extremes impact mortality and morbidity differently.Science advances · 2025Article
- Short-term effect of temperature on cause-specific, sex-specific, and age-specific ambulance dispatches in Czechia: a nationwide time-series analysis.International journal of epidemiology · 2025Article
- Toward a Cohort Perspective of Climate Epidemiology: The Case of Examining Intergenerational Inequalities in Susceptibility to Non-Optimal Temperatures in Japan.Environmental health perspectives · 2025Article
- Non-optimal temperature-attributable mortality and morbidity burden by cause, age and sex under climate and population change scenarios: a nationwide modelling study in Japan.The Lancet regional health. Western Pacific · 2024Article
- Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe impact of temperature on morbidity remains largely unknown. Moreover, extensive evidence indicates contrasting patterns between temperature-mortality and temperature-morbidity associations. A nationwide comparison of the impact of temperature on mortality and morbidity in more specific subgroups is necessary to strengthen understanding and help explore underlying mechanisms by identifying susceptible populations.
objectiveWe performed this study to quantify and compare the impact of temperature on mortality and morbidity in 47 prefectures in Japan.
methodsWe applied a two-stage time-series design with distributed lag nonlinear models and mixed-effect multivariate meta-analysis to assess the association of temperature with mortality and morbidity by causes (all-cause, circulatory, and respiratory) at prefecture and country levels between 2015 and 2019. Subgroup analysis was conducted by sex, age, and regions.
resultsThe patterns and magnitudes of temperature impacts on morbidity and mortality differed. For all-cause outcomes, cold exhibited larger effects on mortality, and heat showed larger effects on morbidity. At specific temperature percentiles, cold (first percentile) was associated with a higher relative risk (RR) of mortality [1.45; 95% confidence interval (CI): 1.39, 1.52] than morbidity (1.33; 95% CI: 1.26, 1.40), as compared to the minimum mortality/morbidity temperature. Heat (99th percentile) was associated with a higher risk of morbidity (1.30; 95% CI: 1.28, 1.33) than mortality (1.04; 95% CI: 1.02, 1.06). For cause-specific diseases, mortality due to circulatory diseases was more susceptible to heat and cold than morbidity. However, for respiratory diseases, both cold and heat showed higher risks for morbidity than mortality. Subgroup analyses suggested varied associations depending on specific outcomes. DISCUSSION: Distinct patterns were observed for the association of temperature with mortality and morbidity, underlying different mechanisms of temperature on different end points, and the differences in population susceptibility are possible explanations. Future mitigation policies and preventive measures against nonoptimal temperatures should be specific to disease outcomes and targeted at susceptible populations. https://doi.org/10.1289/EHP12854.
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