Evidence map›Paper›PMID 38060209›Full record

ArticleLa Medicina del lavoro2023

Occupational Risk Factors for Laryngeal Cancer in Tunisia: A Case Control Study.

Asma Gaddour, Aicha Brahem, Hiba Mosbah, Chaima Sridi, Maroua Saidane, Mouna Belakhdher, Asma Chouchene, Imen Kacem, Maher Maoua, Houda Kalboussi and 4 more

Open access · diamondAbstract read
In one paragraph

Article in La Medicina del lavoro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Asma GaddourDepartment of Occupational Medicine, Faculty of Medicine of Sousse, University of Sousse, Tunisia. asmaagaddour@gmail.com.
Aicha BrahemDepartment of Occupational Medicine, University Farhat Hached hospital, Sousse, Tunisia. aichabrahem@gmail.com.
Hiba MosbahDepartment of Occupational Medicine, Faculty of Medicine of Sousse, University of Sousse, Tunisia. hibamsbh@gmail.com.
Chaima SridiDepartment of Occupational Medicine, University Sahloul hospital, Sousse, Tunisia. chaimasridi@gmail.com.
Maroua SaidaneDepartment of Occupational Medicine, University Farhat Hached hospital, Sousse, Tunisia. marwasaidane@gmail.com.
Mouna BelakhdherENT Department, University Farhat Hached Hospital, Sousse, Tunisia. belakhdhermouna@yahoo.fr.
Asma ChoucheneDepartment of Occupational Medicine, University Farhat Hached Hospital, Sousse, Tunisia. asmachouchen@gmail.com.
Imen KacemDepartment of Occupational Medicine, University Farhat Hached Hospital, Sousse, Tunisia. imenkacem@gmail.com.
Maher MaouaDepartment of Occupational Medicine, University Farhat Hached Hospital, Sousse, Tunisia. mahermaoua@yahoo.fr.
Houda KalboussiDepartment of Occupational Medicine, University Farhat Hached Hospital, Sousse, Tunisia. houdakalb@gmail.com.
Olfa El MaalelDepartment of Occupational Medicine, University Farhat Hached Hospital, Sousse, Tunisia. olfamaalel@gmail.com.
Souheil ChattiDepartment of Occupational Medicine, University Farhat Hached Hospital, Sousse, Tunisia. souheilchati@gmail.com.
Wassim KermaniENT Department, University Farhat Hached Hospital, Sousse, Tunisia. wassimkrmn@gmail.com.
Mrizek NajibDepartment of Occupational Medicine, University Farhat Hached Hospital, Sousse, Tunisia. mrizeknjib@gmail.com.
Hôpital Farhat Hached · TNUniversity of Sousse · TNHôpital Sahloul · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTobacco use and alcohol consumption are the primary risk factors for laryngeal cancer (LC). In most populations, occupational exposures are likely to play a minor role in laryngeal carcinogenesis. We aimed to investigate the association between occupational exposure and laryngeal cancer.

methodsIt is a case-control study that included 140 cases diagnosed between January 2013 and December 2016 and 140 controls matched by sex, age, alcohol consumption, and tobacco consumption.

resultsSignificantly increased risks were found amongst workers of the building sector (OR=4.621; 95% CI [1.826-11.693]) and the mechanical industry sector (OR=5.074; 95% CI [1.425-18.072]). Significant association of laryngeal cancer with various carcinogens was observed such as asbestos (p=0.009; OR=3.68; 95% CI [1.29-10.46]), paint vapors (p=0.005; OR=3.35; 95% CI [1.37-8.16]), solvents (p=0.001; OR=3.29: 95% CI [1.61-6.68]) and cement dust (p=0.003; OR=3.19: 95% CI [1.43-7.12]). After binary logistic regression, cement dust was independently correlated with LC (p=0.042; OR=3.93; 95% CI [1.04-14.78]. The administration sector was associated with decreased risk (p=0.001; OR=0.07; 95% CI [0.03-0.15]) as well as the health sector (p=0.001; OR=0.098; 95% CI [0.02-0.43]).

conclusionsOur results supported the role of occupational factors in developing LC. Further studies enabling an in-depth analysis of occupational exposures are necessary to provide a clearer definition of the etiological associations between single agents and circumstances of exposure and the genesis of LC.

Indexed as

AsbestosLaryngeal NeoplasmsOccupational DiseasesOccupational ExposureCase-Control StudiesDustHumansRisk FactorsTunisiaAsbestosDust

Identifiers

PMID38060209
PMCPMC10731567
OpenAlexW4389452959

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.