Evidence map›Paper›PMID 38060186›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Modeling Mammary Organogenesis from Biological First Principles: A Systems Biology Approach.

Cheryl M Schaeberle, Victoria A Bouffard, Carlos Sonnenschein, Ana M Soto

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cheryl M SchaeberleTufts University School of Medicine, Boston, MA, USA.
Victoria A BouffardTufts University School of Medicine, Boston, MA, USA.
Carlos SonnenscheinTufts University School of Medicine, Boston, MA, USA.
Ana M SotoTufts University School of Medicine, Boston, MA, USA. Ana.Soto@tufts.edu.
Tufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stromal-epithelial interactions mediate mammary gland development and the formation and progression of breast cancer. To study these interactions in vitro, 3D models are essential. We have successfully developed novel 3D in vitro models that allow the formation of mammary gland structures closely resembling those found in vivo and that respond to the hormonal cues that regulate mammary gland morphogenesis and function. Due to their simplicity when compared to in vivo studies, and to their accessibility to visualization in real time, these models are well suited to conceptual and mathematical modeling.

Indexed as

BreastBreast NeoplasmsAnimalsEpithelial CellsFemaleHumansMammary Glands, AnimalMorphogenesisOrganogenesisBreast developmentCalcitriolCarcinogenesisCollagenMorphogenesisVitamin D

Identifiers

PMID38060186
OpenAlexW4389438668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.