Evidence map›Paper›PMID 38059748›Full record

ArticleGut microbes2023

Evolution of

Rahul Unni, Nadia Andrea Andreani, Marie Vallier, Silke S Heinzmann, Jan Taubenheim, Martina A Guggeis, Florian Tran, Olga Vogler, Sven Künzel, Jan-Bernd Hövener and 5 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Deciphering the Implications ofPathogens (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Rahul UnniSection Evolutionary Medicine, Max Planck Institute for Evolutionary Biology, Plön, Germany.ORCID 0000-0002-4656-7542
Nadia Andrea AndreaniSection Evolutionary Medicine, Max Planck Institute for Evolutionary Biology, Plön, Germany.ORCID 0000-0003-0330-9874
Marie VallierSection Evolutionary Medicine, Max Planck Institute for Evolutionary Biology, Plön, Germany.ORCID 0000-0002-7188-7070
Silke S HeinzmannResearch Unit Analytical BioGeoChemistry, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0003-0257-8837
Jan TaubenheimResearch Group Medical Systems Biology, Institute for Experimental Medicine, Kiel University, Kiel, Germany.ORCID 0000-0001-7283-1768
Martina A GuggeisInstitute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.ORCID 0000-0003-4505-3731
Florian TranInstitute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.ORCID 0000-0002-3735-9872
Olga VoglerSection Evolutionary Medicine, Max Planck Institute for Evolutionary Biology, Plön, Germany.ORCID 0000-0001-8930-7671
Sven KünzelSection Evolutionary Medicine, Max Planck Institute for Evolutionary Biology, Plön, Germany.ORCID 0000-0003-4992-5963
Jan-Bernd HövenerSection Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel, Germany.ORCID 0000-0001-7255-7252
Philip RosenstielInstitute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.ORCID 0000-0002-9692-8828
Christoph KaletaResearch Group Medical Systems Biology, Institute for Experimental Medicine, Kiel University, Kiel, Germany.ORCID 0000-0001-8004-9514
Astrid DempfleInstitute of Medical Informatics and Statistics, Kiel University, Kiel, Germany.ORCID 0000-0002-2618-3920
Daniel UnterwegerSection Evolutionary Medicine, Max Planck Institute for Evolutionary Biology, Plön, Germany.ORCID 0000-0001-7459-6386
John F BainesSection Evolutionary Medicine, Max Planck Institute for Evolutionary Biology, Plön, Germany.ORCID 0000-0002-8132-4909
Christian-Albrechts-Universität zu Kiel · DEMax Planck Institute for Evolutionary Biology · DEHelmholtz Zentrum München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a persistent inflammatory condition that affects the gastrointestinal tract and presents significant challenges in its management and treatment. Despite the knowledge that within-host bacterial evolution occurs in the intestine, the disease has rarely been studied from an evolutionary perspective. In this study, we aimed to investigate the evolution of resident bacteria during intestinal inflammation and whether- and how disease-related bacterial genetic changes may present trade-offs with potential therapeutic importance. Here, we perform an

Indexed as

Gastrointestinal MicrobiomeInflammatory Bowel DiseasesAnimalsBacteriaClinical RelevanceEscherichia coliGenotypeHumansInflammationMiceE. colievolutionary trade-offsexperimental evolutionInflammatory bowel disease

Identifiers

PMID38059748
PMCPMC10730162
OpenAlexW4389452715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.