Evidence map›Paper›PMID 38059593›Full record

ArticleOrganic letters2023

Origins of Selectivity in Glycosylation Reactions with Saccharosamine Donors.

Brian P Garreffi, Ryan W Kwok, Mateusz Marianski, Clay S Bennett

Abstract read
In one paragraph

Article in Organic letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Stereoselective Approaches to β-Linked 2-Deoxy Sugars.Molecules (Basel, Switzerland) · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brian P GarreffiDepartment of Chemistry, Tufts University, 62 Talbot Ave, Medford, Massachusetts 02155, United States.
Ryan W KwokDepartment of Chemistry, Hunter College, The City University of New York, 695 Park Ave, New York, New York 10065, United States.ORCID 0000-0001-7245-9142
Mateusz MarianskiDepartment of Chemistry, Hunter College, The City University of New York, 695 Park Ave, New York, New York 10065, United States.ORCID 0000-0002-6566-9931
Clay S BennettDepartment of Chemistry, Tufts University, 62 Talbot Ave, Medford, Massachusetts 02155, United States.ORCID 0000-0001-8070-4988

Funding

Hopping Sugars: molecular mechanism of protonatedglycans rearrangementSC2GM135145 · NIGMS · HUNTER COLLEGE · PI MARIANSKI, MATEUSZ RYSZARD · 2020 to 2022
$468k
NIGMS NIH HHS SC2 GM135145
6 · The paper itself

Abstract

A combination of DFT calculations and experiments is used to describe how the selection of a promoter can control the stereochemical outcome of glycosylation reactions with the deoxy sugar saccharosamine. Depending on the promoter, either α- or β-linked reactive intermediates are formed. These studies show that differential modes of activation lead to the formation of distinct intermediates that undergo highly selective reactions through an S

Identifiers

PMID38059593
PMCPMC11078471

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.