Evidence map›Paper›PMID 38059442›Full record

ArticleEuropean journal of pharmacology2023

Effects of cannabinoid agonists and antagonists in male rats discriminating the synthetic cannabinoid AM2201.

Dalal AlKhelb, Emily L Burke, Alexander Zvonok, Christos Iliopoulos-Tsoutsouvas, Markos-Orestis Georgiadis, Shan Jiang, Thanh C Ho, Spyros P Nikas, Alexandros Makriyannis, Rajeev I Desai

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Cells and Molecules Underpinning Cannabis-Related Variations in Cortical Thickness during Adolescence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Dalal AlKhelbCenter for Drug Discovery, Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA, 02115, USA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 12371, Saudi Arabia.
Emily L BurkeCenter for Drug Discovery, Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA, 02115, USA.
Alexander ZvonokMAK Scientific LLC, 151 South Bedford Street, Burlington, MA, 01803, USA.
Christos Iliopoulos-TsoutsouvasCenter for Drug Discovery, Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA, 02115, USA.
Markos-Orestis GeorgiadisCenter for Drug Discovery, Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA, 02115, USA.
Shan JiangCenter for Drug Discovery, Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA, 02115, USA.
Thanh C HoCenter for Drug Discovery, Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA, 02115, USA.
Spyros P NikasCenter for Drug Discovery, Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA, 02115, USA.
Alexandros MakriyannisCenter for Drug Discovery, Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA, 02115, USA; MAK Scientific LLC, 151 South Bedford Street, Burlington, MA, 01803, USA. Electronic address: a.makriyannis@northeastern.edu.
Rajeev I DesaiCenter for Drug Discovery, Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA, 02115, USA; Department of Psychiatry, Behavioral Biology Program, Integrative Neurochemistry Laboratory, McLean Hospital - Harvard Medical School, Belmont, MA, 02478, USA. Electronic address: r.desai@northeastern.edu.
Northeastern University · US

Funding

Project 3 - In vivo pharmacology of cannabinoid receptor probesP01DA009158 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI Alexandros Makriyannis · 1994 to 2026
$26.0M
MOLECULAR BASIS OF CANNABINOID ACITIVITYR37DA003801 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI MAKRIYANNIS, ALEXANDROS · 1997 to 2006
$3.7M
Antidotes for Acute Cannabinoid IntoxicationR21DA045882 · NIDA · NORTHEASTERN UNIVERSITY · PI MAKRIYANNIS, ALEXANDROS · 2018 to 2019
$416k
NIDA NIH HHS P01 DA009158NIDA NIH HHS R21 DA045882NIDA NIH HHS R37 DA003801
6 · The paper itself

Abstract

The synthetic forms of delta-9-tetrahydrocannabinol (Δ

Indexed as

CannabinoidsDronabinolAnimalsAtropine DerivativesCannabinoid Receptor AgonistsCyclohexanolsDose-Response Relationship, DrugDrug Inverse AgonismFentanylIndolesMaleNaphthalenesRatsReceptor, Cannabinoid, CB11-(5-fluoropentyl)-3-(1-naphthoyl)indole1-pentyl-3-(1-naphthoyl)indole3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanolAtropine DerivativesCannabinoid Receptor AgonistsCannabinoidsCyclohexanolsDronabinolFentanylIndolesNaphthalenesReceptor, Cannabinoid, CB1AM2201 discriminationCannabinoid agonistsCannabinoid antagonistsCannabinoid receptorsCB(1) partial agonistsDrug discriminationΔ(9)-THC

Identifiers

PMID38059442
PMCPMC10704044
OpenAlexW4388162260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.