Evidence map›Paper›PMID 38059306›Full record

Observational studyESC heart failure2024

European Society of Cardiology guidelines and 1 year outcomes of acute heart failure treatment in Central Asia and Europe.

Tamila Abdurashidova, Martin Müller, Sara Schukraft, Nisha Soborun, Barbara Pitta-Gros, John Kikoïne, Henri Lu, Zalina Chazymova, Kanzaada Dzhorupbekova, Medet Beishenkulov and 6 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in ESC heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Safety and efficacy of early beta-blocker initiation in acute heart failure and cardiogenic shock: systematic review and meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Article
  3. Observational
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Tamila AbdurashidovaDivision of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1001, Lausanne, Switzerland.
Martin MüllerDepartment of Emergency Medicine, University Hospital of Bern, University of Bern, Bern, Switzerland.
Sara SchukraftDivision of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1001, Lausanne, Switzerland.
Nisha SoborunDivision of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1001, Lausanne, Switzerland.
Barbara Pitta-GrosDivision of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1001, Lausanne, Switzerland.
John KikoïneDivision of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1001, Lausanne, Switzerland.
Henri LuDivision of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1001, Lausanne, Switzerland.
Zalina ChazymovaCardiac Care Unit, National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan.
Kanzaada DzhorupbekovaDepartment of Statistics, National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan.
Medet BeishenkulovCardiac Care Unit, National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan.
Georgios TzimasDivision of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1001, Lausanne, Switzerland.
Matthias KirschDivision of Cardiac Surgery, Cardiovascular Department, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Peter VollenweiderDepartment of Internal Medicine, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Marie MeanDepartment of Internal Medicine, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Pierre MonneyDivision of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1001, Lausanne, Switzerland.
Roger HullinDivision of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1001, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-5738-1903

Funding

Bundesbehörden der Schweizerischen EidgenossenschaftCentre Hospitalier Universitaire VaudoisSchweizerische Herzstiftung
6 · The paper itself

Abstract

aimsOutcomes reported for patients with hospitalization for acute heart failure (AHF) treatment vary worldwide. Ethnicity-associated characteristics may explain this observation. This observational study compares characteristics and 1-year outcomes of Kyrgyz and Swiss AHF patients against the background of European Society of Cardiology guidelines-based cardiovascular care established in both countries. METHODS AND

resultsThe primary endpoint was 1 year all-cause mortality (ACM); the secondary endpoint was 1 year ACM or HF-related rehospitalization. A total of 538 Kyrgyz and 537 Swiss AHF patients were included. Kyrgyz patients were younger (64.0 vs. 83.0 years, P < 0.001); ischaemic or rheumatic heart disease and chronic obstructive pulmonary disease were more prevalent (always P < 0.001). In Swiss patients, smoking, dyslipidaemia, hypertension, and atrial flutter/fibrillation were more frequent (always P ≤ 0.035); moreover, left ventricular ejection fraction (LVEF) was higher (47% vs. 36%; P < 0.001), and >mild aortic stenosis was more prevalent (P < 0.001). Other valvular pathologies were more prevalent in Kyrgyz patients (P < 0.001). At discharge, more Swiss patients were on vasodilatory treatment (P < 0.006), while mineralocorticoid receptor antagonists (P = 0.001), beta-blockers (P = 0.001), or loop diuretics (P < 0.001) were less often prescribed. In Kyrgyz patients, unadjusted odds for the primary and secondary endpoints were lower [odds ratio (OR) 0.68, 95% confidence interval (CI): 0.51-0.90, P = 0.008; OR 0.72, 95% CI: 0.56-0.91, P = 0.006, respectively]. After adjustment for age and LVEF, no difference remained (primary endpoint: OR 1.03, 95% CI: 0.71-1.49, P = 0.894; secondary endpoint: OR 0.82, 95% CI: 0.60-1.12, P = 0.206).

conclusionsOn the background of identical guidelines, age- and LVEF-adjusted outcomes were not different between Central Asian and Western European AHF patients despite of large ethnical disparity.

Indexed as

CardiologyHeart FailureAsiaHumansStroke VolumeVentricular Function, LeftAcute heart failureESC guidelinesEthnicityOutcome

Identifiers

PMID38059306
PMCPMC10804142

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.