Evidence map›Paper›PMID 38059120›Full record

ArticleBioactive materials2024

Engineered smart materials for RNA based molecular therapy to treat Glioblastoma.

Ravi Raj Singh, Indranil Mondal, Taskeen Janjua, Amirali Popat, Ritu Kulshreshtha

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Dual-functional nanoplatform for simultaneous degradation of circRNAJournal of Zhejiang University. Science. B · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Ravi Raj SinghDepartment of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, New Delhi, India.
Indranil MondalDepartment of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, New Delhi, India.
Taskeen JanjuaSchool of Pharmacy, The University of Queensland, Brisbane, QLD, 4072, Australia.
Amirali PopatSchool of Pharmacy, The University of Queensland, Brisbane, QLD, 4072, Australia.
Ritu KulshreshthaDepartment of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, New Delhi, India.
Indian Institute of Technology Delhi · INThe University of Queensland · AUUniversity of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is an aggressive malignancy of the central nervous system (CNS) that remains incurable despite the multitude of improvements in cancer therapeutics. The conventional chemo and radiotherapy post-surgery have only been able to improve the prognosis slightly; however, the development of resistance and/or tumor recurrence is almost inevitable. There is a pressing need for adjuvant molecular therapies that can successfully and efficiently block tumor progression. During the last few decades, non-coding RNAs (ncRNAs) have emerged as key players in regulating various hallmarks of cancer including that of GBM. The levels of many ncRNAs are dysregulated in cancer, and ectopic modulation of their levels by delivering antagonists or overexpression constructs could serve as an attractive option for cancer therapy. The therapeutic potential of several types of ncRNAs, including miRNAs, lncRNAs, and circRNAs, has been validated in both

Indexed as

Gene therapyGlioblastoma (GBM)NanocarriersNanoparticlesNon-coding RNAs (ncRNA)Nucleic acid therapyOligonucleotide therapyRNA delivery system

Identifiers

PMID38059120
PMCPMC10696434
OpenAlexW4389066247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.