Evidence map›Paper›PMID 38059041›Full record

ArticleNanoscale advances2023

Hybrid AuNPs-3MPS-MTX nanosystem and its evaluation for treating cervical cancer and melanoma.

M J Hernández-Esparza, Ilaria Fratoddi, Sara Cerra, K Juarez-Moreno, R Huirache-Acuña

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M J Hernández-EsparzaFacultad de Ingeniería Química, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria C.P. 58060 Morelia Mexico rafael.huirache@umich.mx.
Ilaria FratoddiDepartment of Chemistry, University Sapienza of Rome p. Aldo Moro 5 00185 Rome Italy.ORCID https://orcid.org/0000-0002-5172-0636
Sara CerraDepartment of Chemistry, University Sapienza of Rome p. Aldo Moro 5 00185 Rome Italy.ORCID https://orcid.org/0000-0002-5549-9406
K Juarez-MorenoCentro de Física Aplicada y Tecnología Avanzada, Universidad Nacional Autónoma de México Mexico kjuarez@fata.unam.mx.ORCID https://orcid.org/0000-0002-6171-8601
R Huirache-AcuñaFacultad de Ingeniería Química, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria C.P. 58060 Morelia Mexico rafael.huirache@umich.mx.ORCID https://orcid.org/0000-0002-1395-0887

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research presents an evaluation of a hybrid material based on gold nanoparticles (AuNPs), stabilized with the thiol 3-mercapto-propanesulfonate (3MPS) and loaded with the methotrexate drug (MTX). The AuNPs-3MPS-MTX nanosystem was tested for the treatment of cervical cancer and melanoma, using the B16-F10 melanoma and HeLa cell lines. The tests performed on cell cultures assessed the efficiency of the studied nanosystem on tumor cells, as well as its toxicology.

Identifiers

PMID38059041
PMCPMC10696946

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.