Evidence map›Paper›PMID 38059013›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2023

Short-Term Benefits of Smoking Cessation Improve Respiratory Function and Metabolism in Smokers.

Aldo Pezzuto, Alberto Ricci, Michela D'Ascanio, Alba Moretta, Giuseppe Tonini, Noemi Calabrò, Valeria Minoia, Alessia Pacini, Giuliana De Paolis, Eleonora Chichi and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Risk and Protective Factors of COPD Among Smokers: A Cross-Sectional Study Using NHANES Database.International journal of chronic obstructive pulmonary disease · 2025
    Article
  18. Observational
  19. Article
  20. Evidence-Based Synthesis for Practice: Lifestyle Interventions in Type 2 Diabetes with Obesity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Aldo PezzutoDepartment of Cardiovascular and Respiratory Sciences, S Andrea Hospital, Sapienza University, Rome, Italy.ORCID 0000-0002-6626-2260
Alberto RicciDepartment of Cardiovascular and Respiratory Sciences, S Andrea Hospital, Sapienza University, Rome, Italy.ORCID 0000-0002-1718-1587
Michela D'AscanioDepartment of Cardiovascular and Respiratory Sciences, S Andrea Hospital, Sapienza University, Rome, Italy.ORCID 0000-0002-2141-7409
Alba MorettaDepartment of Cardiovascular and Respiratory Sciences, S Andrea Hospital, Sapienza University, Rome, Italy.
Giuseppe ToniniOncology Department, Campus Bio-Medico University, Rome, Italy.
Noemi CalabròDepartment of Cardiovascular and Respiratory Sciences, S Andrea Hospital, Sapienza University, Rome, Italy.
Valeria MinoiaDepartment of Cardiovascular and Respiratory Sciences, S Andrea Hospital, Sapienza University, Rome, Italy.ORCID 0009-0008-7437-2663
Alessia PaciniDepartment of Cardiovascular and Respiratory Sciences, S Andrea Hospital, Sapienza University, Rome, Italy.ORCID 0009-0001-1699-8595
Giuliana De PaolisDepartment of Cardiovascular and Respiratory Sciences, S Andrea Hospital, Sapienza University, Rome, Italy.
Eleonora ChichiDepartment of Cardiovascular and Respiratory Sciences, S Andrea Hospital, Sapienza University, Rome, Italy.
Elisabetta CaricoClinical and Molecular Medicine Department, S Andrea Hospital, Sapienza University, Rome, Italy.
Antonella TammaroDepartment of Neuroscience- NESMOS, S.Andrea Hospital, Sapienza University, Rome, Italy.
Azienda Ospedaliera Sant'Andrea · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cigarette smoke exposure is the main preventable cause of chronic obstructive pulmonary disease (COPD). Airflow limitation is closely associated with smoking exposure. Smoking could also interfere with lipid metabolism. Aim: To determine the respiratory functional and metabolic changes after smoking cessation in smokers in the short term. Methods: All patients were current smokers. They were assessed by spirometry and questionnaires such as COPD assessment test(CAT), modified Medical Research Council (mMRC) test for dyspnea, Fagestrom's test for nicotine dependence. Exhaled CO was detected in order to evaluate smoking exposure and smoking cessation (normal value<7 ppm). A blood sampling was eventually taken for vitamin D and cholesterol assay. All patients underwent therapy with counselling and varenicline as first-line treatment according to its schedule. Detection time: at baseline and one month after smoking cessation. Results: All patients quit smoking during treatment. The mean age was 62 with a prevalence of males. The analysis revealed the following mean values at baseline: CAT mean score was 15, pack-years 35.5, Fagestrom's Test mean score 5.0. The West's value was 8.5, whereas Body mass index (BMI) was 25.5.Cigarette daily consumption mean value was 22.5. The comparison before and at follow up one month after smoking cessation about functional and metabolic parameters, show us the following results: FEV 1 was increased by 200 mL (p<0.02), FEF 25/75 was improved as well as mMRC test. The eCO was dropped to as low as 8 ppM. Interestingly the vitamin D level was increased from 25 to 28 ng/mL without any support therapy. The cholesterol total level was reduced and CAT value and DLCO were also significantly improved. Conclusion: Quit smoking is useful to improve symptoms, respiratory function and metabolic parameters in the short term.

Indexed as

Pulmonary Disease, Chronic ObstructiveSmoking CessationCholesterolFemaleHumansMaleMiddle AgedSmokersVitamin DCholesterolVitamin Dairflow limitationlipid metabolismsmoking cessation

Identifiers

PMID38059013
PMCPMC10697086
OpenAlexW4389241114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.