Evidence map›Paper›PMID 38058725›Full record

ArticleArchives of medical science : AMS2023

Therapeutic properties of isoliquiritigenin with molecular modeling studies: investigation of anti-pancreatic acinar cell tumor and HMG-CoA reductase inhibitor activity for treatment of hypercholesterolemia.

Jihua Li, Fengfeng Zhu, Weiguo Xu, Ping Che

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of medical science : AMS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Licorice-induced severe hypokalemic rhabdomyolysis.Archives of medical science : AMS · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jihua LiInterventional Radiology Department of Zhuhai Hospital affiliated with Jinan University (Zhuhai People's Hospital), Zhuhai, Guangdong, China.
Fengfeng ZhuDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of University of South China, Hengyang, Hunan, China.
Weiguo XuInterventional Radiology Department of Zhuhai Hospital affiliated with Jinan University (Zhuhai People's Hospital), Zhuhai, Guangdong, China.
Ping CheDepartment of General Surgery, Chongqing Hechuan District Maternal and Child Health Care Hospital, Chongqing, China.
Jinan University · CNChongqing Maternal and Child Health Hospital · CNUniversity of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Isoliquiritigenin, one of the components in the root of Material and methods: HMG-CoA reductase activity was determined according to the method described by Takahashi Results: In our study, the inhibitory activity of isoliquiritigenin towards HMG-CoA reductase showed a lower value of IC Conclusions: The cells treated with isoliquiritigenin were assessed by MTT assay for 48 h as regards the cytotoxicity and anti-human pancreatic acinar cell tumor properties in normal (HUVEC) and human pancreatic acinar cell tumor cell lines, i.e. 266-6, TGP49, and TGP47. The IC

Indexed as

HMG-COA reductasehuman pancreatic acinar cell tumorisoliquiritigeninmolecular docking

Identifiers

PMID38058725
PMCPMC10696990
OpenAlexW4206207725

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.