Evidence map›Paper›PMID 38058699›Full record

ArticleArchives of medical science : AMS2023

Introducing a novel chemotherapeutic drug formulated with anthraflavic acid for treating human breast carcinoma and type 2 diabetes mellitus.

Gang Zhao, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Milton Wainwright

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Gang ZhaoDepartment of Breast Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.
Arunachalam ChinnathambiDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Tahani Awad AlahmadiDepartment of Pediatrics, College of Medicine and King Khalid University Hospital, King Saud University, Medical City,Riyadh, Saudi Arabia.
Milton WainwrightDepartment of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.
First Hospital of Jilin University · CNKing Saud Medical City · SAKing Saud University · SAUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Molecular docking as a versatile theoretical method was used to investigate the biological activities of anthraflavic acid in the presence of α-amylase. The outcomes revealed that anthraflavic acid has a considerable binding affinity to the enzyme with a docking score of -7.913 kcal/mol. These outcomes were further evaluated with free binding energy calculations, and it was concluded that anthraflavic acid could be a potential inhibitor for α-amylase. Material and methods: Anthraflavic acid was explored in anti-human breast carcinoma tests. The Results: The IC Conclusions: It seems the anti-human breast carcinoma effect of recent nanoparticles is due to their antioxidant effects.

Indexed as

anthraflavic acidcytotoxichuman breast carcinomamolecular dockingα-amylase

Identifiers

PMID38058699
PMCPMC10696992
OpenAlexW3195301619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.