Evidence map›Paper›PMID 38058645›Full record

ArticleHeliyon2023

Ameliorating effects of

Mohammad Abbas Bejeshk, Amir Hashem Aminizadeh, Mohammad Amin Rajizadeh, Fahimeh Rostamabadi, Fatemeh Bagheri, Mohammad Khaksari, Maryam Azimi

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mohammad Abbas BejeshkDepartment of Physiology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Amir Hashem AminizadehFaculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Mohammad Amin RajizadehPhysiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran.
Fahimeh RostamabadiNoncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran.
Fatemeh BagheriPathology and Stem Cell Research Center, Department of Pathology, Afzalipour School of Medicine, Kerman, Iran.
Mohammad KhaksariDepartment of Physiology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Maryam AzimiGastroenterology and Hepatology Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Kerman University of Medical Sciences · IRBam University of Medical Sciences · IRStem Cell Technology Research Center · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Ulcerative colitis (UC) is a chronic recurrent inflammatory disease of the large intestine and rectum. The disease is characterized by oxidative stress and severe inflammation. Research has shown the anti-oxidative and anti-inflammatory effects induced by consuming the Methods: A total number of 50 male rats were selected and randomly assigned to five groups of 10 rats each. Colitis was induced in rats by enemas with a 4 % acetic acid solution. Four days after the colitis induction, the rats were orally treated for the next 4 days with saline or a combination of A. arabica and O. basilicum (1000 mg/kg) or sulfasalazine (100 mg/kg). Results: Acetic acid-induced colitis increased the colon's macroscopic and histopathological damage scores; increased colon levels of MDA (Malondialdehyde), MPO (Myeloperoxidase), TNF-α (Tissue necrosis factor α), IL6 (Interleukin 6), and IL17 (Interleukin 17); and decreased SOD (Superoxide Dismutase), GPx (Glutathione Peroxidase), and IL10 (Interleukin 10) levels in the treated rats compared with the control group (P < 0.001). Overall, a combination of Conclusion:

Indexed as

Acacia arabicaAcetic acid-induced ulcerative colitis inflammationBasil seedGum ArabicOcimum basilicumStress oxidative

Identifiers

PMID38058645
PMCPMC10696014
OpenAlexW4388682042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.