Evidence map›Paper›PMID 38058495›Full record

ArticleJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada2023

Highly pathogenic avian influenza: Unprecedented outbreaks in Canadian wildlife and domestic poultry.

Christian Renaud, Andrea Osborn, Elizabeth Jane Parmley, Todd F Hatchette, J LeBlanc, Jeffrey Scott Weese, Vikram Misra, Deborah Yamamura, Sarah Forgie, Shane Renwick and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Highly Pathogenic Avian Influenza H5N1 in Cats (Animals : an open access journal from MDPI · 2025
    Review
  6. A rapid review of the avian influenza PB2 E627K mutation in human infection studies.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  7. Article
  8. Article
  9. It's time to apply outbreak response best practices to avian influenza: A national call to action.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Christian RenaudDepartment of Microbiology, Infectiology and Immunology, & Department of Pediatrics, Université de Montréal, Montréal, Québec, Canada.
Andrea OsbornCanadian Food Inspection Agency, Canada.
Elizabeth Jane ParmleyDepartment of Population Medicine, University of Guelph, Guelph, Ontario, Canada.
Todd F HatchetteDivision of Microbiology, Department of Pathology and Laboratory Medicine, Central Zone Nova Scotia Health, Halifax, Nova Scotia, Canada.
J LeBlancDivision of Microbiology, Department of Pathology and Laboratory Medicine, Central Zone Nova Scotia Health, Halifax, Nova Scotia, Canada.
Jeffrey Scott WeeseCentre for Public Health and Zoonoses, University of Guelph, Guelph, Ontario, Canada.
Vikram MisraDepartment of Veterinary Microbiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Deborah YamamuraDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Sarah ForgieDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Shane RenwickCanadian Veterinary Medical Association, Canada.
Duncan WebsterDivision of Infectious Diseases, Faculty of Medicine, Dalhousie Medicine New Brunswick, Saint John, New Brunswick, Canada.
Samira MubarekaDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
AMMI Canada One Health working group
Nova Scotia Health Authority · CAUniversity of Guelph · CACanadian Food Inspection Agency · CACanadian Veterinary Medical Association · CAMcMaster University · CASaint John Regional Hospital · CAUniversité de Montréal · CAUniversity of Alberta · CAUniversity of Saskatchewan · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canada experienced a wave of HPAI H5N1 outbreaks in the spring of 2022 with millions of wild and farmed birds being infected. Seabird mortalities in Canada have been particularly severe on the Atlantic Coast over the summer of 2022. Over 7 million birds have been culled in Canada, and outbreaks continue to profoundly affect commercial bird farms across the world. This new H5N1 virus can and has infected multiple mammalian species, including skunks, foxes, bears, mink, seals, porpoises, sea lions, and dolphins. Viruses with mammalian adaptations such as the mutations PB2-E627K, E627V, and D701N were found in the brain of various carnivores in Europe and Canada. To date this specific clade of H5N1 virus has been identified in less than 10 humans. At the ground level, awareness should be raised among frontline practitioners most likely to encounter patients with HPAI.

Indexed as

avian fluH5N1influenzamammalian adaptationOne Health

Identifiers

PMID38058495
PMCPMC10697099
OpenAlexW4389453178

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.