ArticleMicrobiome research reports2023
MEGAnnotator2: a pipeline for the assembly and annotation of microbial genomes.
Article in Microbiome research reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetic strategies for sex-biased persistence of gut microbes across human life.Nature communications · 2023Pooled it
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- Assessment of genome evolution inmSystems · 2026Article
- Unveiling the genetic landscape and motility-associated functions of Type IV pili in theMicrobiome research reports · 2026Article
- Host interactions ofApplied and environmental microbiology · 2025Article
- Compiling an early life human gut microbiome atlas and identification of key microbial drivers.NPJ biofilms and microbiomes · 2025Article
- Diversity and functional characterization of HNH endonucleases encoded by lactococcalMicrobial genomics · 2025Article
- Quorum Sensing via Autoinducer-2 Promotes Colonisation and Host Adaptation in B. bifidum PRL2010.Microbial biotechnology · 2025Article
- Functional modulation of the human gut microbiome by bacteria vehicled by cheese.Applied and environmental microbiology · 2025Article
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- Characterization of aApplied and environmental microbiology · 2024Article
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- From raw milk cheese to the gut: investigating the colonization strategies ofApplied and environmental microbiology · 2024Article
- TheApplied and environmental microbiology · 2024Article
- Ecology- and genome-based identification of theApplied and environmental microbiology · 2024Article
- Comparative genome analysis of microbial strains marketed for probiotic interventions: an extension of the Integrated Probiotic Database.Microbiome research reports · 2024Article
- Comprehensive insights from composition to functional microbe-based biodiversity of the infant human gut microbiota.NPJ biofilms and microbiomes · 2023Article
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Authors and funding
7 authors.
Funding
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Abstract
The reconstruction of microbial genome sequences by bioinformatic pipelines and the consequent functional annotation of their genes' repertoire are fundamental activities aiming at unveiling their biological mechanisms, such as metabolism, virulence factors, and antimicrobial resistances. Here, we describe the development of the MEGAnnotator2 pipeline able to manage all next-generation sequencing methodologies producing short- and long-read DNA sequences. Starting from raw sequencing data, the updated pipeline can manage multiple analyses leading to the assembly of high-quality genome sequences and the functional classification of their genetic repertoire, providing the user with a useful report constituting features and statistics related to the microbial genome. The updated pipeline is fully automated from the installation to the delivery of the output, thus requiring minimal bioinformatics knowledge to be executed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.