Evidence map›Paper›PMID 38057910›Full record

ArticleNeurological research and practice2023

Rendezvous intervention using combined surgical carotid endarterectomy followed by endovascular thrombectomy in patients with acute tandem occlusions: a proof-of-concept experience at a tertiary care center.

Norma J Diel, Stefan T Gerner, Omar Alhaj Omar, Johannes Kalder, Enikö Manz, Paula R Keschenau, Tobias Struffert, Thomas Brueckner, Hagen B Huttner, Thorsten R Doeppner

Open access · diamondAbstract read
In one paragraph

Article in Neurological research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Mechanical thrombectomy failure in anterior and posterior circulation stroke: current results from a high-volume comprehensive center.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Norma J Diel *Department of Neurology, University Hospital Giessen, Klinikstrasse 33, 35392, Giessen, Germany.
Stefan T Gerner *Department of Neurology, University Hospital Giessen, Klinikstrasse 33, 35392, Giessen, Germany.
Omar Alhaj OmarDepartment of Neurology, University Hospital Giessen, Klinikstrasse 33, 35392, Giessen, Germany.
Johannes KalderDepartment of Adult and Pediatric Cardiovascular Surgery, University Hospital Giessen, Giessen, Germany.
Enikö ManzDepartment of Adult and Pediatric Cardiovascular Surgery, University Hospital Giessen, Giessen, Germany.
Paula R KeschenauDepartment of Adult and Pediatric Cardiovascular Surgery, University Hospital Giessen, Giessen, Germany.
Tobias StruffertDepartment of Neuroradiology, University Hospital Giessen, Giessen, Germany.
Thomas BruecknerDepartment of Neuroradiology, University Hospital Giessen, Giessen, Germany.
Hagen B HuttnerDepartment of Neurology, University Hospital Giessen, Klinikstrasse 33, 35392, Giessen, Germany.
Thorsten R DoeppnerDepartment of Neurology, University Hospital Giessen, Klinikstrasse 33, 35392, Giessen, Germany. Thorsten.Doeppner@neuro.med.uni-giessen.de.
Universitätsklinikum Gießen und Marburg · DEBrain (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndovascular thrombectomy (EVT) is highly effective in acute stroke patients with intracranial large vessel occlusion (LVO), however, presence of concomitant cervical occlusion of the internal carotid artery (ICA) may limit the endovascular access. This study describes feasibility and efficacy of a surgical carotid access (cutdown) to perform interdisciplinary recanalization therapy including carotid endarterectomy (CEA) followed by EVT for recanalization of intracranial LVO in stroke patients with tandem occlusions.

methodsWe identified stroke patients with tandem occlusions who underwent a combined surgical-endovascular approach over a 5-year period. Surgical cutdown was provided by a cardiovascular surgery team at the angio-suite followed by EVT performed by the neuroradiological team. Demographics, stroke characteristics, treatments including antithrombotic management, procedure times, and clinical follow-up were assessed.

resultsFour patients with acute stroke because of tandem occlusions received CEA followed by EVT (two patients after frustrating femoral catheterization, two as first-line approach). Successful recanalization (TICI ≥ 2b) via endovascular thrombectomy was achieved in all patients at a median of 28 min after successful surgical CEA. Intraprocedural complication was observed in one case (25%; i.e. ICA dissection).

conclusionsThis small study provides evidence that a combined interdisciplinary approach of CEA followed by EVT in the angio-suite in acute stroke patients with tandem occlusions is a feasible procedure in patients otherwise not accessible to endovascular recanalizing therapy and, therefore, high likelihood of developing large hemispheric infarction. Prospective data are warranted to identify patients who benefit from this combined approach as first-line therapy.

Indexed as

Carotid endarterectomyEndovascular thrombectomyRescue therapyTandem occlusion

Identifiers

PMID38057910
PMCPMC10701999
OpenAlexW4389409905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.