Evidence map›Paper›PMID 38057881›Full record

ArticleCritical care (London, England)2023

Comparing outcomes of out-of-hospital cardiac arrest patients with initial shockable rhythm in Singapore and Osaka using population-based databases.

Yohei Okada, Nur Shahidah, Yih Yng Ng, Michael Y C Chia, Han Nee Gan, Benjamin S H Leong, Desmond R Mao, Wei Ming Ng, Nausheen Edwin, Takeyuki Kiguchi and 4 more

Abstract read
In one paragraph

Article in Critical care (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Latent class analysis for identification of sub-phenotypes predicting prognosis in hospitalized out-of-hospital cardiac arrest.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yohei OkadaDuke-NUS Medical School, Health Services and Systems Research, Singapore, Singapore. yokada-kyf@umin.ac.jp.
Nur ShahidahDepartment of Emergency Medicine, Singapore General Hospital, Singapore, Singapore.
Yih Yng NgLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Michael Y C ChiaEmergency Department, Tan Tock Seng Hospital, Singapore, Singapore.
Han Nee GanAccident and Emergency, Changi General Hospital, Singapore, Singapore.
Benjamin S H LeongEmergency Medicine Department, National University Hospital, Singapore, Singapore.
Desmond R MaoDepartment of Acute and Emergency Care, Khoo Teck Puat Hospital, Singapore, Singapore.
Wei Ming NgEmergency Medicine Department, Ng Teng Fong General Hospital, Singapore, Singapore.
Nausheen EdwinDepartment of Emergency Medicine, Sengkang General Hospital, Singapore, Singapore.
Takeyuki KiguchiDepartment of Preventive Services, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Norihiro NishiokaDepartment of Preventive Services, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tetsuhisa KitamuraDivision of Environmental Medicine and Population Sciences, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.
Taku IwamiDepartment of Preventive Services, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Marcus Eng Hock OngDuke-NUS Medical School, Health Services and Systems Research, Singapore, Singapore.

Funding

Japan Society for the Promotion of Science JP22K21143Ministry of Health, Health Services Research Grant HSRG/0021/2012National Medical Research Council (NMRC/CSA/024/2010, NMRC/CSA/0049/2013 and NMRC/CSASI/014/2017)
6 · The paper itself

Abstract

backgroundPrevious research indicated outcomes among refractory out-of-hospital cardiac arrest (OHCA) patients with initial shockable rhythm were different in Singapore and Osaka, Japan, possibly due to the differences in access to extracorporeal cardiopulmonary resuscitation. However, this previous study had a risk of selection bias. To address this concern, this study aimed to evaluate the outcomes between Singapore and Osaka for OHCA patients with initial shockable rhythm using only population-based databases.

methodsThis was a secondary analysis of two OHCA population-based databases in Osaka and Singapore, including adult OHCA patients with initial shockable rhythm. A machine-learning-based prediction model was derived from the Osaka data (n = 3088) and applied to the PAROS-SG data (n = 2905). We calculated the observed-expected ratio (OE ratio) for good neurological outcomes observed in Singapore and the expected derived from the data in Osaka by dividing subgroups with or without prehospital ROSC.

resultsThe one-month good neurological outcomes in Osaka and Singapore among patients with prehospital ROSC were 70% (791/1,125) and 57% (440/773), and among patients without prehospital ROSC were 10% (196/1963) and 2.8% (60/2,132). After adjusting patient characteristics, the outcome in Singapore was slightly better than expected from Osaka in patients with ROSC (OE ratio, 1.067 [95%CI 1.012 to 1.125]), conversely, it was worse than expected in patients without prehospital ROSC (OE ratio, 0.238 [95%CI 0.173 to 0.294]).

conclusionThis study showed the outcomes of OHCA patients without prehospital ROSC in Singapore were worse than expected derived from Osaka data even using population-based databases. (249/250 words).

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesOut-of-Hospital Cardiac ArrestAdultDatabases, FactualHumansJapanRegistriesSingapore

Identifiers

PMID38057881
PMCPMC10699037

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.