Evidence map›Paper›PMID 38057795›Full record

ArticleBMC complementary medicine and therapies2023

Cancer patients' behaviors and attitudes toward natural health products.

Audrey Schils, Anne-Sophie Lechon, Sarah Rondeaux, Florence Souard, Jean-Luc Van Laethem, Stephanie Pochet, Veronique Mathieu, Carine De Vriese

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07745205 (HEALTHS - Holistic Evaluation of Approaches to Long-term Health and Survivorship), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07745205 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

HEALTHS - Holistic Evaluation of Approaches to Long-term Health and Survivorship (Focus Phytotherapy) A Single-center, Minimal-risk, Two-phase Study Including a Quantitative Observational Survey and an Interventional Mixed-methods Component With Focus Group Sessions.

TypeinterventionalSponsorJules Bordet InstituteRan2026 to 2027Enrolled500ConditionsAdult Cancer Survivors, Adult Cancer PatientsArmsInterventional mixed-methods evaluation of cancer patient's behaviour regarding CAMs (focus groups), Quantitative evaluation of cancer patient's use of CAM's
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Audrey SchilsDepartment of Pharmacotherapy and Pharmaceutics, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Boulevard du Triomphe 9040, 1050, Brussels, Belgium.
Anne-Sophie LechonDepartment of Pharmacotherapy and Pharmaceutics, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Boulevard du Triomphe 9040, 1050, Brussels, Belgium.
Sarah RondeauxDepartment of Pharmacotherapy and Pharmaceutics, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Boulevard du Triomphe 9040, 1050, Brussels, Belgium.
Florence SouardDepartment of Pharmacotherapy and Pharmaceutics, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Boulevard du Triomphe 9040, 1050, Brussels, Belgium.
Jean-Luc Van LaethemDepartment of Gastroenterology and Digestive Oncology, Erasme University Hospital, Université Libre de Bruxelles (ULB), Route de Lennik 808, 1070, Brussels, Belgium.
Stephanie PochetDepartment of Pharmacotherapy and Pharmaceutics, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Boulevard du Triomphe 9040, 1050, Brussels, Belgium.
Veronique MathieuDepartment of Pharmacotherapy and Pharmaceutics, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Boulevard du Triomphe 9040, 1050, Brussels, Belgium.
Carine De VrieseDepartment of Pharmacotherapy and Pharmaceutics, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Boulevard du Triomphe 9040, 1050, Brussels, Belgium. carine.de.vriese@ulb.be.
Université Libre de Bruxelles · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNatural health products (NHPs), including vitamins, minerals, and herbal supplements, are the most common complementary and alternative medicine (CAM) among cancer patients. Our survey determined the attitudes and behaviors of cancer patients toward natural complementary therapies that should be considered to implement an integrative approach in the future.

methodsOur survey was conducted in four hospitals in Belgium. Questionnaires were posted online from October 2020 to October 2021 for cancer patients. Descriptive statistics were used to analyze the data. A [Formula: see text] test was applied to study the type of NHP consumed according to diagnosis time. Fischer's exact test compared patients who had changed their consumption since diagnosis and those who had not.

resultsOut of 349 questionnaires collected, only 59 met all inclusion criteria. 83.1 % of the patients agreed that conventional medicine (CM) could benefit from complementary therapies, but they did not estimate (72.3 % of the patients) that those latter are more effective than conventional medicine. More than half of the patients used five or more NHPs. The most frequent NHPs consumed daily were vitamins (64.4 %), followed by other products (i.e., probiotics, gemmotherapy, birch sap and omega 3/6) (42.4 %) and herbs (40.7 %). Almost all patients started taking NHPs before their cancer diagnosis, but 72.7 % have changed their consumption significantly (p = 0.009) since their diagnosis. Boosting the immune system (79.7 %) and limiting conventional treatment side effects (76.9 %) were the most common reasons for NHPs' use. 74.4 % of the patients did not take complementary therapies to delay or avoid conventional treatment.

conclusionsThe combination and high diversity of NHPs consumption highlight the importance of educating patients and healthcare providers (HCPs) about the risk of drug interactions associated with these natural products. Most cancer patients are more interested in using this non-mainstream medicine to complement their conventional treatment than as an alternative. Knowing the patients' reasons and understanding patients' attitudes toward NHPs will be essential for HCPs to address NHPs' use.

Indexed as

Biological ProductsComplementary TherapiesNeoplasmsDietary SupplementsHumansVitamin AVitamin KVitaminsBiological ProductsVitamin AVitamin KVitaminsAttitudesBehaviorsBelgiumCancerComplementary and alternative medicineDescriptive studyIntegrative oncologyNatural health productsOnline questionnaire

Identifiers

PMID38057795
PMCPMC10698981
OpenAlexW4389392694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.