Evidence map›Paper›PMID 38057704›Full record

ArticleBMC infectious diseases2023

The experience and reflections of GC labs as an independent clinical laboratory to the COVID-19 pandemic in South Korea.

You La Jeon, Sang Gon Lee, Eun Hee Lee, Sungwook Song, O-Jin Lee, Un Yeong Go, Ga-Young Chun, Hyun Mi Choi, Jin Young Choi

Abstract read
In one paragraph

Article in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

You La JeonDepartment of Laboratory Medicine, Green Cross Laboratories, 107, Ihyeon-Ro 30Beon-Gil, Giheung-Gu, Yongin-Si, Gyeonggi-Go, South Korea.
Sang Gon Lee *Department of Laboratory Medicine, Green Cross Laboratories, 107, Ihyeon-Ro 30Beon-Gil, Giheung-Gu, Yongin-Si, Gyeonggi-Go, South Korea. sglee@gclabs.co.kr.
Eun Hee Lee *Department of Laboratory Medicine, Green Cross Laboratories, 107, Ihyeon-Ro 30Beon-Gil, Giheung-Gu, Yongin-Si, Gyeonggi-Go, South Korea. ehlee@gclabs.co.kr.
Sungwook SongDepartment of Laboratory Medicine, Green Cross Laboratories, 107, Ihyeon-Ro 30Beon-Gil, Giheung-Gu, Yongin-Si, Gyeonggi-Go, South Korea.
O-Jin LeeDepartment of Laboratory Medicine, Green Cross Laboratories, 107, Ihyeon-Ro 30Beon-Gil, Giheung-Gu, Yongin-Si, Gyeonggi-Go, South Korea.
Un Yeong GoDepartment of Laboratory Medicine, Green Cross Laboratories, 107, Ihyeon-Ro 30Beon-Gil, Giheung-Gu, Yongin-Si, Gyeonggi-Go, South Korea.
Ga-Young ChunDepartment of Laboratory Medicine, Green Cross Laboratories, 107, Ihyeon-Ro 30Beon-Gil, Giheung-Gu, Yongin-Si, Gyeonggi-Go, South Korea.
Hyun Mi ChoiDepartment of Laboratory Medicine, Green Cross Laboratories, 107, Ihyeon-Ro 30Beon-Gil, Giheung-Gu, Yongin-Si, Gyeonggi-Go, South Korea.
Jin Young ChoiDepartment of Laboratory Medicine, Green Cross Laboratories, 107, Ihyeon-Ro 30Beon-Gil, Giheung-Gu, Yongin-Si, Gyeonggi-Go, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmid the COVID-19 pandemic, extensive testing was undertaken by independent clinical laboratories (ICLs), yet limited research exists on this matter. Drawing from Green Cross Laboratories (GC Labs)' pandemic response experience, this study seeks to offer insights for preparation for the next pandemic.

methodsThis retrospective study analyzed the outcomes of SARS-CoV-2 real-time reverse transcription polymerase chain reaction (SARS-CoV-2 rRT PCR) tests administered by GC Labs for COVID-19 diagnosis, upon request by different organizations, between February 2020 and April 2022. The distribution of institutions that requested the tests, the type of tests, and the positive rate were analyzed. We investigated resource allocation details.

resultsICLs were responsible for conducting 85.6% of all tests carried out under South Korea's COVID-19 testing policy during the pandemic. The availability of free testing regardless of symptoms led to a significant increase in the use of pooled tests, which accounted for more than 80% of all tests conducted after August 2021. The gender and age distribution of COVID-19 cases nationwide and GC Labs' positive cases were similar. When we analyzed the positive rate by requesting organizations during the COVID-19 pandemic, despite an overall nationwide positivity rate of 35%, high-risk facilities exhibited a positivity rate of less than 5% by maintaining preemptive testing. The most notable increase in resources during the pandemic was seen in human resource input.

conclusionsSouth Korea's ICLs were able to conduct large volumes of testing during the COVID-19 pandemic because of their logistics and computer systems, scalable testing space, and trained testing personnel. They also had the flexibility to bring in additional resources to expand testing capacity because they are specialized testing organizations. Hence, ICLs could execute the pooled test that the government had introduced for extensive general population screening. The preemptive periodic testing of high-risk populations kept the positive rate much lower than in the general population. This study's findings will aid in refining mass testing-based policies for the next pandemic.

Indexed as

COVID-19Clinical Laboratory TechniquesCOVID-19 TestingHumansLaboratories, ClinicalPandemicsRepublic of KoreaRetrospective StudiesSARS-CoV-2ControlCOVID-19LaboratoriesSARS-CoV-2

Identifiers

PMID38057704
PMCPMC10699033

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.