Evidence map›Paper›PMID 38057634›Full record

ArticleAnalytical and bioanalytical chemistry2024

Spatial distribution of trace metals and associated transport proteins during bacterial infection.

Raquel Gonzalez de Vega, David Clases, Bliss A Cunningham, Katherine Ganio, Stephanie L Neville, Christopher A McDevitt, Philip A Doble

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raquel Gonzalez de VegaThe Atomic Medicine Initiative, University of Technology Sydney, Broadway, New South Wales, Australia.ORCID http://orcid.org/0000-0002-9806-9633
David ClasesThe Atomic Medicine Initiative, University of Technology Sydney, Broadway, New South Wales, Australia.ORCID http://orcid.org/0000-0003-3880-9385
Bliss A CunninghamDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-4654-1972
Katherine GanioDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-7360-6466
Stephanie L NevilleDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-7298-9335
Christopher A McDevittDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-1596-4841
Philip A DobleThe Atomic Medicine Initiative, University of Technology Sydney, Broadway, New South Wales, Australia. Philip.Doble@uts.edu.au.ORCID http://orcid.org/0000-0002-8472-1301

Funding

Australian Research Council DP190102361Australian Research Council DP220100713Garnett Passe and Rodney Williams Memorial Foundation Junior FellowshipMiklos Family Philanthropic Grant
6 · The paper itself

Abstract

Innate immune systems alter the concentrations of trace elements in host niches in response to invading pathogens during infection. This work reports the interplay between d-block metal ions and their associated biomolecules using hyphenated elemental techniques to spatially quantify both elemental distributions and the abundance of specific transport proteins. Here, lung tissues were collected for analyses from naïve and Streptococcus pneumoniae-infected mice fed on a zinc-restricted or zinc-supplemented diet. Spatiotemporal distributions of manganese (

Indexed as

Bacterial InfectionsTrace ElementsAnimalsCarrier ProteinsCopperMass SpectrometryMiceZincCarrier ProteinsCopperTrace ElementsZincHyphenated techniquesImmunohistochemistryIsotope dilution analysisLA-ICP-MSQuantificationSEC-ICP-MSStreptococcus pneumoniae

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.