Evidence map›Paper›PMID 38057619›Full record

ReviewWorld journal of microbiology & biotechnology2023

Cytochrome P450 for environmental remediation: catalytic mechanism, engineering strategies and future prospects.

Haichen Yang, Fei Yu, Zhihui Qian, Tongwang Huang, Tao Peng, Zhong Hu

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Elucidating the metabolic pathway and initial degradation gene forApplied and environmental microbiology · 2025
    Article
  5. Whole-Genome Sequence Analysis ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  6. Electron transfer in biological systems.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Haichen YangDepartment of Biology, Shantou University, Shantou, 515063, Guangdong, People's Republic of China.
Fei YuDepartment of Biology, Shantou University, Shantou, 515063, Guangdong, People's Republic of China.
Zhihui QianDepartment of Biology, Shantou University, Shantou, 515063, Guangdong, People's Republic of China.
Tongwang HuangDepartment of Biology, Shantou University, Shantou, 515063, Guangdong, People's Republic of China.
Tao PengDepartment of Biology, Shantou University, Shantou, 515063, Guangdong, People's Republic of China. tpeng@stu.edu.cn.
Zhong HuDepartment of Biology, Shantou University, Shantou, 515063, Guangdong, People's Republic of China. hzh@stu.edu.cn.
Shantou University · CN

Funding

Guangdong Natural Science Foundation-General Project 2023A1515012065National Natural Science Foundation of China 32370132National Natural Science Foundation of China 42276158
6 · The paper itself

Abstract

Environmental pollution is a global concern. Various organic compounds are released into the environment through wastewater, waste gas, and waste residue, ultimately accumulating in the environment and the food chain. This poses a significant threat to both human health and ecology. Currently, a growing body of research has demonstrated that microorganisms employ their Cytochrome P450 (CYP450) system for biodegradation, offering a crucial approach for eliminating these pollutants in environmental remediation. CYP450, a ubiquitous catalyst in nature, includes a vast array of family members distributed widely across various organisms, including bacteria, fungi, and mammals. These enzymes participate in the metabolism of diverse organic compounds. Furthermore, the rapid advancements in enzyme and protein engineering have led to increased utilization of engineered CYP450s in environmental remediation, enhancing their efficiency in pollutant removal. This article presents an overview of the current understanding of various members of the CYP450 superfamily involved in transforming organic pollutants and the engineering of biodegrading CYP450s. Additionally, it explores the catalytic mechanisms, current practical applications of CYP450-based systems, their potential applications, and the prospects in bioremediation.

Indexed as

Environmental PollutantsEnvironmental Restoration and RemediationAnimalsBiodegradation, EnvironmentalCytochrome P-450 Enzyme SystemHumansMammalsProtein EngineeringCytochrome P-450 Enzyme SystemEnvironmental PollutantsBiotransformationCatalytic mechanismCytochrome P450DiversityOrganic pollutants

Identifiers

PMID38057619
OpenAlexW4389450768

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.