Evidence map›Paper›PMID 38057602›Full record

ArticleJournal of bone and mineral metabolism2024

Can TBS reference values be a valid indicator for clinical vertebral fracture? A cross-sectional study.

Yasuyuki Omichi, Noriaki Mima, Keizo Wada, Ryo Okada, Yasuaki Tamaki, Daisuke Hamada, Tomohiro Goto, Masatoshi Morimoto, Tsutomu Enomoto, Hiroki Hayashi and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of bone and mineral metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yasuyuki OmichiDepartment of Orthopedics, Tokushima Municipal Hospital, 2-34 Kitajousanjima, Tokushima, 770-0812, Japan. aizenaha2008@yahoo.co.jp.ORCID http://orcid.org/0000-0002-4358-9199
Noriaki MimaDepartment of Orthopedics, Mima Hospital, Yoshinogawa, Japan.
Keizo WadaDepartment of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Ryo OkadaDepartment of Orthopedics, Tokushima Prefectural Central Hospital, Tokushima, Japan.
Yasuaki TamakiDepartment of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Daisuke HamadaDepartment of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Tomohiro GotoDepartment of Orthopedics, Tokushima Municipal Hospital, 2-34 Kitajousanjima, Tokushima, 770-0812, Japan.
Masatoshi MorimotoDepartment of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Tsutomu EnomotoDepartment of Radiology, Mima Hospital, Yoshinogawa, Japan.
Hiroki HayashiDepartment of Radiology, Mima Hospital, Yoshinogawa, Japan.
Koichi SairyoDepartment of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Tokushima University · JPMiwa Hospital · JPTokushima Municipal Hospital · JPTokushima Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTrabecular bone score (TBS) is partially independent of fracture risk. Reference values for TBS have not been established in official guidelines, and thus clinicians often have difficulty interpreting TBS results. This study aimed to investigate whether reference values for TBS could be a valid indicator for clinical vertebral fracture (CVF). MATERIALS AND

methodsThis cross-sectional study involved 231 women with CVF and 563 women without CVF aged 60-90 years who underwent dual-energy X-ray absorptiometry during 2019-2023. They were divided into osteoporosis, osteopenia, and normal groups according to bone mineral density of the lumbar spine. Reference values for TBS were defined as low (≤ 1.23), intermediate (1.23-1.31), and high (≥ 1.31).

resultsAmong patients without anti-osteoporosis treatment (n = 476), the proportion with low TBS was 36.7% in the CVF group and 10.7% in the control group. The proportion with CVF was higher in the low TBS group than in the intermediate and high TBS groups, especially in the osteoporosis group (p < 0.001). The odds ratio for CVF was higher in the low TBS group than in the intermediate and high especially in patients with normal BMD and osteoporosis. The TBS cut-off values for incidence of CVF in the osteoporosis, osteopenia, and normal groups were 1.224, 1.319, and 1.322, respectively.

conclusionsThe reference value for low TBS (≤ 1.23) was useful as an indicator for CVF, especially in patients with osteoporosis. It is expected that reference values for TBS will be established in official guidelines in the future.

Indexed as

OsteoporosisOsteoporotic FracturesSpinal FracturesAbsorptiometry, PhotonBone DensityCancellous BoneCross-Sectional StudiesFemaleHumansLumbar VertebraeReference ValuesBone mineral densityClinical vertebral fractureDistributionReference valueTrabecular bone score

Identifiers

PMID38057602
OpenAlexW4389390512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.