Evidence map›Paper›PMID 38057559›Full record

ArticleEye (London, England)2024

Real-world experience of implementing the MOLES score in a virtual choroidal naevi clinic at a tertiary referral centre.

Nicholas O T Rees, Sarah Schimansky, Gemma Bizley, Lina Kobayter

Abstract read
In one paragraph

Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Imaging-based machine learning for the diagnosis and prognosis of uveal melanoma: a systematic review and meta analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Nicholas O T ReesMedical Retina Service, Bristol Eye Hospital, Lower Maudlin Street, Bristol, BS1 2LX, United Kingdom. nicholas.rees@nhs.net.ORCID http://orcid.org/0000-0002-8197-8849
Sarah SchimanskyMedical Retina Service, Bristol Eye Hospital, Lower Maudlin Street, Bristol, BS1 2LX, United Kingdom.
Gemma BizleyMedical Retina Service, Bristol Eye Hospital, Lower Maudlin Street, Bristol, BS1 2LX, United Kingdom.
Lina KobayterMedical Retina Service, Bristol Eye Hospital, Lower Maudlin Street, Bristol, BS1 2LX, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe MOLES score has been validated to clinically differentiate choroidal naevi from melanomas by ocular oncologists and community optometrists. However, its utility in a virtual choroidal naevi clinic at a tertiary eye hospital without specialist ocular oncology services has not yet been evaluated.

methodsA retrospective case review of 385 choroidal lesions in the virtual choroidal naevus clinic at Bristol Eye Hospital during January-March 2020 and April-August 2021 was performed. Choroidal lesions were assessed using the TFSOM-UHHD risk factor index and MOLES score, respectively. For both study periods, clinical outcome and adherence data were analysed.

resultsChoroidal lesions scored higher with the TFSOM-UHHD index (median 2) compared to the MOLES score (median 0; p < 0.001). Median required follow-up duration was 2 years for lesions assessed with the TFSOM-UHHD index, and 0 years for those graded with the MOLES score. Overall, 215 patients were appropriately discharged to community optometrists based on their MOLES score. Imaging requirements for the TFSOM-UHHD index and MOLES score protocols were met in 69.1% and 94.8% of cases, respectively.

conclusionThe MOLES score was easily implemented in a virtual choroidal naevus clinic, with good adherence. It increased clinic capacity by facilitating appropriate discharges of low-risk naevi to community monitoring, allowing finite and specialist hospital-based services to monitor higher-risk naevi more closely.

Indexed as

Choroid NeoplasmsMolesNevusNevus, PigmentedSkin NeoplasmsAnimalsHumansRetrospective StudiesTertiary Care Centers

Identifiers

PMID38057559
PMCPMC11009328

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.