Evidence map›Paper›PMID 38057268›Full record

ReviewJournal of Zhejiang University. Science. B2023

Micropeptides: origins, identification, and potential role in metabolism-related diseases.

Yirui Lu, Yutong Ran, Hong Li, Jiao Wen, Xiaodong Cui, Xiaoyun Zhang, Xiumei Guan, Min Cheng

Open access · greenAbstract readReview
In one paragraph

Review in Journal of Zhejiang University. Science. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yirui Lu
Yutong Ran
Hong Li
Jiao Wen
Xiaodong Cui
Xiaoyun Zhang
Xiumei Guan
Min ChengSchool of Basic Medicine Sciences, Weifang Medical University, Weifang 261053, China. mincheng@wfmc.edu.cn.
Weifang Medical University · CN

Funding

the National Natural Science Foundation of China 81870237
6 · The paper itself

Abstract

With the development of modern sequencing techniques and bioinformatics, genomes that were once thought to be noncoding have been found to encode abundant functional micropeptides (miPs), a kind of small polypeptides. Although miPs are difficult to analyze and identify, a number of studies have begun to focus on them. More and more miPs have been revealed as essential for energy metabolism homeostasis, immune regulation, and tumor growth and development. Many reports have shown that miPs are especially essential for regulating glucose and lipid metabolism and regulating mitochondrial function. MiPs are also involved in the progression of related diseases. This paper reviews the sources and identification of miPs, as well as the functional significance of miPs for metabolism-related diseases, with the aim of revealing their potential clinical applications.

Indexed as

Metabolic DiseasesPeptidesGenomeGlucoseHumansOpen Reading FramesGlucosePeptidesEnergy metabolismMicropeptidesMitochondriaNoncoding RNA (ncRNA)Small open reading frame (sORF)

Identifiers

PMID38057268
PMCPMC10710913
OpenAlexW4389452424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.