Evidence map›Paper›PMID 38057169›Full record

ReviewTrends in biotechnology2024

Advances in 3D bioprinting for urethral tissue reconstruction.

Daniel Booth, Ronak Afshari, Mahsa Ghovvati, Kaavian Shariati, Renea Sturm, Nasim Annabi

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Trends in biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Description of the Human Penile Urethra Epithelium.Medicina (Kaunas, Lithuania) · 2025
    Article
  8. Review
  9. Emergent biotechnology applications in urology: a mini review.Frontiers in bioengineering and biotechnology · 2025
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Daniel BoothDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Ronak AfshariDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Mahsa GhovvatiDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Kaavian ShariatiDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Renea SturmDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: rsturm@mednet.ucla.edu.
Nasim AnnabiDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: nannabi@ucla.edu.
University of California, Los Angeles · US

Funding

Engineering highly elastic surgical sealants with hemostatic propertiesR01HL140618 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ANNABI, NASIM, KHADEMHOSSEINI, ALI · 2018 to 2021
$2.8M
Engineering a naturally derived and highly adhesive surgical sealantR01EB023052 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ANNABI, NASIM, KHADEMHOSSEINI, ALI · 2017 to 2022
$2.4M
Highly Elastic Biomaterial Development for Urethral ApplicationK08DK134868 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Renea Sturm · 2023 to 2026
$680k
NHLBI NIH HHS R01 HL140618NIBIB NIH HHS R01 EB023052NIDDK NIH HHS K08 DK134868
6 · The paper itself

Abstract

Urethral conditions affect children and adults, increasing the risk of urinary tract infections, voiding and sexual dysfunction, and renal failure. Current tissue replacements differ from healthy urethral tissues in structural and mechanical characteristics, causing high risk of postoperative complications. 3D bioprinting can overcome these limitations through the creation of complex, layered architectures using materials with location-specific biomechanical properties. This review highlights prior research and describes the potential for these emerging technologies to address ongoing challenges in urethral tissue engineering, including biomechanical and structural mismatch, lack of individualized repair solutions, and inadequate wound healing and vascularization. In the future, the integration of 3D bioprinting technology with advanced biomaterials, computational modeling, and 3D imaging could transform personalized urethral surgical procedures.

Indexed as

BioprintingPrinting, Three-DimensionalTissue EngineeringUrethraAnimalsBiocompatible MaterialsHumansPlastic Surgery ProceduresTissue ScaffoldsBiocompatible Materials3D bioprintingbiomaterialstissue engineeringurethraurological disease

Identifiers

PMID38057169
PMCPMC11669461
OpenAlexW4389330086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.