Evidence map›Paper›PMID 38056930›Full record

ArticleBMJ case reports2023

Surprise diagnosis of acquired von Willebrand syndrome in a patient previously thought to have type III von Willebrand disease: evaluation and periprocedural management.

Katherine Ismei Zhou, Sargam Kapoor, Oluwatoyosi Adefunke Onwuemene

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Katherine Ismei ZhouDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, USA.ORCID http://orcid.org/0000-0001-6442-0475
Sargam KapoorDivision of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.ORCID http://orcid.org/0000-0003-0689-6197
Oluwatoyosi Adefunke OnwuemeneDivision of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA toyosi.onwuemene@duke.edu.ORCID http://orcid.org/0000-0001-7266-7101
Duke Medical Center · US

Funding

TRANSFUSION MEDICINE AND RELATED AREAST32HL007057 · NHLBI · DUKE UNIVERSITY · PI Gowthami M Arepally · 1985 to 2026
$10.6M
NHLBI NIH HHS T32 HL007057
6 · The paper itself

Abstract

Acquired von Willebrand syndrome (AVWS) is a rare disorder that is characterised by an acquired deficiency of von Willebrand factor. AVWS was suspected in a patient with type III von Willebrand disease (VWD) who did not respond to factor replacement therapy. Given the crucial implications for management, we describe this patient's clinical presentation, diagnosis and periprocedural management. To facilitate pericardiocentesis, periprocedural management included steroids, intravenous immunoglobulin and factor replacement therapy. In other patients with suspected immune-mediated AVWS, a similar approach may be effective. This case also highlights the importance of distinguishing AVWS from inherited VWD.

Indexed as

von Willebrand DiseasesDiagnosis, DifferentialHumansImmunoglobulins, Intravenousvon Willebrand FactorImmunoglobulins, Intravenousvon Willebrand FactorHaematology (incl blood transfusion)Malignant and Benign haematologyMedical management

Identifiers

PMID38056930
PMCPMC10711894
OpenAlexW4389373190

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.