Evidence map›Paper›PMID 38056909›Full record

ArticleLife science alliance2024

IMPA1 dependent regulation of phosphatidylinositol 4,5-bisphosphate and calcium signalling by lithium.

Sankhanil Saha, Harini Krishnan, Padinjat Raghu

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Mechanisms of Lithium Action: The Old and New Findings.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sankhanil SahaNational Centre for Biological Sciences-TIFR GKVK Campus, Bangalore, India.ORCID https://orcid.org/0000-0001-6198-1605
Harini KrishnanNational Centre for Biological Sciences-TIFR GKVK Campus, Bangalore, India.
Padinjat RaghuNational Centre for Biological Sciences-TIFR GKVK Campus, Bangalore, India praghu@ncbs.res.in.ORCID https://orcid.org/0000-0003-3578-6413
National Centre for Biological Sciences · IN

Funding

Wellcome Trust
6 · The paper itself

Abstract

Lithium (Li) is widely used as a mood stabilizer to treat bipolar affective disorder. However, the molecular targets of Li that underpin its therapeutic effect remain unresolved. Inositol monophosphatase (IMPA1) is an enzyme involved in phosphatidylinositol 4,5-bisphosphate (PIP

Indexed as

LithiumPhosphatidylinositolsCalciumCalcium SignalingHumansPhosphoric Monoester HydrolasesCalciumLithiummyo-inositol-1 (or 4)-monophosphatasePhosphatidylinositolsPhosphoric Monoester Hydrolases

Identifiers

PMID38056909
PMCPMC10700560
OpenAlexW4389398106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.