ArticleCurrent biology : CB2023
A cluster of neuropeptide S neurons regulates breathing and arousal.
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Article in Current biology : CB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 12% of its field
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Neuropeptide S modulation of learning and memory: a systematic review.Behavioral and brain functions : BBF · 2026Pooled it
- Thalamus and consciousness: a systematic review on thalamic nuclei associated with consciousness.Frontiers in neurology · 2025Pooled it
- Article
- A projection atlas of excitatory and inhibitory inputs to the preBötzinger complex: substrates for multimodal breathing control.Journal of neurophysiology · 2026Article
- Electrophysiological characterization of neuropeptide S-expressing neurons in the periLC: influence of the female estrous cycle on neuronal excitability in mice.Pflugers Archiv : European journal of physiology · 2026Article
- A Distinct Subpopulation of Extended Amygdala Neurons Drives Food Intake.Biological psychiatry global open science · 2026Article
- Nps-Expressing Neurons Receive Extensive Input From Auditory Brainstem Nuclei.The Journal of comparative neurology · 2026Article
- A Distinct Subpopulation of Extended Amygdala Neurons Drives Food Intake.bioRxiv : the preprint server for biology · 2025Article
- Multimodal Breathing Control: Pontomedullary Mechanisms and Current Perspectives.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- NPS neurons receive extensive input from auditory brainstem nuclei.bioRxiv : the preprint server for biology · 2025Article
- Dopaminergic signaling to ventral striatum neurons initiates sniffing behavior.Nature communications · 2025Article
- Triangular Causality Among Pulmonary Hypertension, Sleep Disorders, and Brain Structure at the Genetic Level: A Mendelian Randomization Study Focused on the Lung-Brain Axis.Nature and science of sleep · 2025Article
- Efferent projections of Nps-expressing neurons in the parabrachial region.The Journal of comparative neurology · 2024Article
- A neuronal cluster involved in arousal and breathing.Nature reviews. Neuroscience · 2024Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 1 country.
Christopher Caleb AngelakosDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.
Kasey S GirvenDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA; University of Washington Center for the Neurobiology of Addiction, Pain, and Emotion, Seattle, WA 98195, USA; Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.
Yin LiuDepartment of Biochemistry, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Oscar C GonzalezDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.
Keith R MurphyDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.
Kim J JenningsDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.
William J GiardinoDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.
Larry S ZweifelDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA; Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.
Azra SukoDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA; University of Washington Center for the Neurobiology of Addiction, Pain, and Emotion, Seattle, WA 98195, USA; Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.
Richard D PalmiterDepartment of Biochemistry, Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.
Stewart D ClarkDepartment of Pharmacology and Toxicology, State University of New York at Buffalo, Buffalo, NY 14214, USA.
Mark A KrasnowDepartment of Biochemistry, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Michael R BruchasDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA; University of Washington Center for the Neurobiology of Addiction, Pain, and Emotion, Seattle, WA 98195, USA; Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.
Luis de LeceaDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA. Electronic address: llecea@stanford.edu.
Neurosciences Institute · USStanford University · USUniversity of Washington · USWashington Center · USHoward Hughes Medical Institute · USUniversity at Buffalo, State University of New York · US
Funding
University of Washington Center of Excellence in Opioid Addiction ResearchP30DA048736 · NIDA · UNIVERSITY OF WASHINGTON · PI Charles Chavkin · 2019 to 2026
$13.0MVECTOR COREP30NS069375 · NINDS · STANFORD UNIVERSITY · PI STEINBERG, GARY K · 2011 to 2019
$6.3MDecoding Locus Coeruleus Neural Circuits and Signaling In Negative AffectR01MH112355 · NIMH · WASHINGTON UNIVERSITY · PI Michael R. Bruchas · 2016 to 2026
$5.3MNeuropeptide S and arousalR01MH128140 · NIMH · STANFORD UNIVERSITY · PI DE LECEA, LUIS · 2021 to 2025
$2.9MFunctional Heterogeneity of Hypocretin NeuronsR01MH116470 · NIMH · STANFORD UNIVERSITY · PI APPELBAUM, LIOR YOSEF, DE LECEA, LUIS · 2019 to 2023
$2.4MSmall molecule biased agonists of the NPS receptorR56MH114313 · NIMH · RESEARCH TRIANGLE INSTITUTE · PI CLARK, STEWART DONALDSON, RUNYON, SCOTT P · 2017 to 2018
$1.4MDecoding Neuropeptide S Modulation of Reward Seeking BehaviorF32DA055480 · NIDA · UNIVERSITY OF WASHINGTON · PI GIRVEN, KASEY SHEA · 2022 to 2022
$72kNeuropeptide Cortistatin: A potential neocortical regulator of sleep homeostasisF32HL154792 · NHLBI · STANFORD UNIVERSITY · PI ANGELAKOS, CHRISTOPHER CALEB · 2020 to 2020
$56kNHLBI NIH HHS F32 HL154792NIDA NIH HHS F32 DA055480NIDA NIH HHS P30 DA048736NIMH NIH HHS R01 MH112355NIMH NIH HHS R01 MH116470NIMH NIH HHS R01 MH128140NIMH NIH HHS R56 MH114313NINDS NIH HHS P30 NS069375
Abstract
Neuropeptide S (NPS) is a highly conserved peptide found in all tetrapods that functions in the brain to promote heightened arousal; however, the subpopulations mediating these phenomena remain unknown. We generated mice expressing Cre recombinase from the Nps gene locus (Nps
Indexed as
NeuropeptidesAnimalsArousalBrainMiceNeuronsRespirationSleepWakefulnessNeuropeptidesarousalbreathingfiber photometrylateral parabrachialneuropeptide circuitsneuropeptide Sneuropeptide S receptorrespirationsleep
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.