Evidence map›Paper›PMID 38056425›Full record

ArticleCell metabolism2023

All hands on deck: Adipocytes lept-in to drive nerve regeneration.

Alina Rashid, Qin Wang, Yuanquan Song

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alina RashidRaymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Qin WangRaymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Yuanquan SongRaymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: songy2@chop.edu.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · US

Funding

Training Program in Neurodevelopmental DisabilitiesT32NS007413 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI AMELIA J EISCH, ERIC D MARSH · 1998 to 2026
$8.9M
Glial metabolic status regulates axon regeneration in the central nervous systemR01NS126541 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI Yuanquan Song · 2023 to 2026
$2.3M
Targeting Atr to promote regeneration and functional recovery after neural injuryR01NS107392 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI SONG, YUANQUAN · 2018 to 2022
$1.9M
NINDS NIH HHS R01 NS107392NINDS NIH HHS R01 NS126541NINDS NIH HHS T32 NS007413
6 · The paper itself

Abstract

The glial metabolic state instructs nerve regeneration. In this issue of Cell Metabolism, Sundaram, Schütza, Schröter, et al. demonstrate that nerve injury induces adipocytes-glia signaling via leptin, thereby modulating glial metabolism and driving nerve regeneration.

Indexed as

Nerve RegenerationNeurogliaAdipocytesSignal Transduction

Identifiers

PMID38056425
PMCPMC10823866
OpenAlexW4389331979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.