Evidence map›Paper›PMID 38055739›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Essential role of MFSD1-GLMP-GIMAP5 in lymphocyte survival and liver homeostasis.

Xue Zhong, James J Moresco, Jolene K Diedrich, Antonio M Pinto, Jeffrey A SoRelle, Jianhui Wang, Katie Keller, Sara Ludwig, Eva Marie Y Moresco, Bruce Beutler and 1 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Quantitative temporal analysis of pancreatic islet T lymphocyte and macrophage infiltration heralded by serum IgE in congenic BioBreeding (BB) Gimap5Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  2. Article
  3. Review
  4. Disruption of the ZFP574-THAP12 complex suppresses B cell malignancies in mice.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Article
  6. Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Essential role of MFSD1-GLMP-GIMAP5 in lymphocyte survival and liver homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xue ZhongCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.
James J MorescoCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.ORCID 0000-0003-1178-1642
Jolene K DiedrichDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037.
Antonio M PintoDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037.
Jeffrey A SoRelleCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Jianhui WangCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Katie KellerCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Sara LudwigCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Eva Marie Y MorescoCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.ORCID 0000-0002-2049-7291
Bruce BeutlerCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.ORCID 0000-0002-3639-246X
Jin Huk ChoiCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.ORCID 0000-0003-2483-4379
The University of Texas Southwestern Medical Center · USSalk Institute for Biological Studies · USScripps Research Institute · US

Funding

Automated Forward Genetic Analysis of Adaptive ImmunityR01AI125581 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI BRUCE A BEUTLER · 2016 to 2026
$19.5M
NIAID NIH HHS R01 AI125581
6 · The paper itself

Abstract

We detected ENU-induced alleles of

Indexed as

GTP-Binding ProteinsLymphopeniaHomeostasisHumansLiverLymphocytesProteomicsGTP-Binding Proteinsextramedullary hematopoiesisGIMAP5GLMPMFSD1MTOR

Identifiers

PMID38055739
PMCPMC10723049
OpenAlexW4389386888

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.