Evidence map›Paper›PMID 38055107›Full record

ArticleNeuroscience bulletin2024

Three-phase Enriched Environment Improves Post-stroke Gait Dysfunction via Facilitating Neuronal Plasticity in the Bilateral Sensorimotor Cortex: A Multimodal MRI/PET Analysis in Rats.

Yun Lu, Ziyue Lin, Mingcong Li, Yuming Zhuang, Binbin Nie, Jianfeng Lei, Yuanyuan Zhao, Hui Zhao

Open access · greenAbstract read
In one paragraph

Article in Neuroscience bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yun LuSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Ziyue LinSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Mingcong LiSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Yuming ZhuangSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Binbin NieBeijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, 100049, China.
Jianfeng LeiMedical Imaging Laboratory of Core Facility Center, Capital Medical University, Beijing, 100069, China.
Yuanyuan ZhaoMedical Imaging Laboratory of Core Facility Center, Capital Medical University, Beijing, 100069, China.
Hui ZhaoSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China. zhaohuishouyi@ccmu.edu.cn.
Capital Medical University · CNInstitute of High Energy Physics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The three-phase Enriched Environment (EE) paradigm has been shown to promote post-stroke functional improvement, but the neuronal mechanisms are still unclear. In this study, we applied a multimodal neuroimaging protocol combining magnetic resonance imaging (MRI) and positron emission tomography (PET) to examine the effects of post-ischemic EE treatment on structural and functional neuroplasticity in the bilateral sensorimotor cortex. Rats were subjected to permanent middle cerebral artery occlusion. The motor function of the rats was examined using the DigiGait test. MRI was applied to investigate the EE-induced structural modifications of the bilateral sensorimotor cortex. [

Indexed as

Magnetic Resonance ImagingNeuronal PlasticityPositron-Emission TomographyRats, Sprague-DawleySensorimotor CortexAnimalsEnvironmentGait Disorders, NeurologicInfarction, Middle Cerebral ArteryMaleMultimodal ImagingRatsStrokeAxonogenesisEnriched environmentFunctional connectivityGait functionGlucose metabolismMicroenvironmental moleculesNeuronal plasticityStructural integrity

Identifiers

PMID38055107
PMCPMC11178725
OpenAlexW4389397686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.