Evidence map›Paper›PMID 38055062›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2023

Potentially inappropriate end-of-life care and its association with relatives' well-being: a systematic review.

Laurien Ham, Ellis Slotman, Carolien Burghout, Natasja Jh Raijmakers, Lonneke V van de Poll-Franse, Lia van Zuylen, Heidi P Fransen

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laurien HamDepartment of Research & Development, The Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501, DB, Utrecht, The Netherlands. l.ham@iknl.nl.
Ellis SlotmanDepartment of Research & Development, The Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501, DB, Utrecht, The Netherlands.
Carolien BurghoutDepartment of Hemato-Oncology, Jeroen Bosch Hospital, Den Bosch, The Netherlands.
Natasja Jh RaijmakersDepartment of Research & Development, The Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501, DB, Utrecht, The Netherlands.
Lonneke V van de Poll-FranseDepartment of Research & Development, The Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501, DB, Utrecht, The Netherlands.
Lia van ZuylenDepartment of Medical Oncology, Amsterdam University Medical Centers, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Heidi P FransenDepartment of Research & Development, The Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501, DB, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePotentially inappropriate end-of-life cancer care (e.g., frequent hospital admission and emergency room visits in the last month of life) is known to be associated with a poorer quality of life of patients, but research on its association with the well-being of relatives is scarce. The aim of this systematic literature review was to evaluate the association between potentially inappropriate end-of-life cancer care and relatives' well-being.

methodsWe conducted a systematic search and review, and reported according to the PRISMA guideline, on the association between potentially inappropriate end-of-life cancer care and well-being of relatives before and after the death of their loved one. Pubmed, PsycInfo, Embase, and CINAHL were searched for studies published from January 2000 to July 2022. Studies' quality was assessed using the Critical Appraisal Checklists from the Joanne Briggs Institute (JBI).

resultsWe identified eight studies including 10,062 relatives (59-79% female, mean age 46-61 years, 29-72% partner). Potentially inappropriate end-of-life cancer care was associated with poorer well-being of relatives including lower quality of life, higher burden of depressive symptoms, more regret, and more feelings of unpreparedness for the patient's death.

conclusionPotentially inappropriate cancer care at the end-of-life is associated with poorer well-being of relatives before and after the death of their loved one. This emphasizes the importance of avoiding potentially inappropriate end-of-life cancer care, as it is both associated with poorer outcomes for relatives and patients. However, the number of studies examining this association is small, and more research is needed in this area.

Indexed as

Quality of LifeTerminal CareChecklistDeathEmergency Service, HospitalFemaleHumansMaleMiddle AgedCancerEnd-of-lifePotentially inappropriate careRelativesSystematic reviewWell-being

Identifiers

PMID38055062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.