Evidence map›Paper›PMID 38054971›Full record

ArticleMicrobial genomics2023

A critical role for iron and zinc homeostatic systems in the evolutionary adaptation of

Joy R Paterson, Joshua M Wadsworth, Ping Hu, Gary J Sharples

Open access · goldAbstract read
In one paragraph

Article in Microbial genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Third-Generation Cephalosporin-Resistant UropathogenicThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Joy R PatersonDepartment of Biosciences, Durham University, Durham, UK.
Joshua M WadsworthDepartment of Biosciences, Durham University, Durham, UK.
Ping HuProcter and Gamble, Mason Business Center, Cincinnati, Ohio 45040, USA.
Gary J SharplesDepartment of Biosciences, Durham University, Durham, UK.
Durham University · GBProcter & Gamble (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Host nutritional immunity utilizes metal deprivation to help prevent microbial infection. To investigate bacterial adaptation to such restrictive conditions, we conducted experimental evolution with two metal sequestering agents. Ethylenediaminetetraacetic acid (EDTA) and diethylenetriamine pentamethylene phosphonic acid (DTPMP) were selected as ligands because they differentially affect cellular levels of iron, manganese and zinc in

Indexed as

Escherichia coliIronAnti-Bacterial AgentsEdetic AcidZincAnti-Bacterial AgentsEdetic AcidIronZincacid tolerancecadCchelating agentsfepAmetal homeostasisyeiR

Identifiers

PMID38054971
PMCPMC10763504
OpenAlexW4389376774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.