Evidence map›Paper›PMID 38054903›Full record

ReviewPathologica2023

COVID-19 and lung cancer.

Laura Melocchi, Maria Cecilia Mengoli, Giuseppe Bogina, Mattia Facchetti, Federica Migliorati, Laura Gandolfi, Giulio Rossi

Open access · diamondAbstract readReview
In one paragraph

Review in Pathologica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Laura MelocchiPathology Unit, Services Area, Fondazione Poliambulanza Hospital Institute, Brescia, Italy.
Maria Cecilia MengoliOperative Unit of Pathology, Azienda USL/IRCCS, Reggio Emilia, Italy.
Giuseppe BoginaDepartment of Pathology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Italy.
Mattia FacchettiDepartment of Pathology, ASST Spedali Civili, Brescia, Italy.
Federica MiglioratiPathology Unit, Services Area, Fondazione Poliambulanza Hospital Institute, Brescia, Italy.
Laura GandolfiPathology Unit, Services Area, Fondazione Poliambulanza Hospital Institute, Brescia, Italy.
Giulio RossiPathology Unit, Services Area, Fondazione Poliambulanza Hospital Institute, Brescia, Italy.
Fondazione Poliambulanza Istituto Ospedaliero · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITOspedale Sacro Cuore Don Calabria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 pandemic had affected health services around the world, also reducing the diagnosis of lung cancer. On the other hand, examination of surgical specimens in patients with lung cancer and SARS-CoV-2 gave the opportunity to evidence early histologic features related to this emerging pandemic. Different prioritization of health organizations during COVID-19 pandemic resulted in a significant decline of lung cancer screening (up to 56%), delayed diagnosis (up to 30-40%) and higher advanced stage, with some exceptions (i.e., Canada). Increased use of stereotactic radiation treatments in stage I-IIA have been noticed in better-organized health systems. Surgical specimens performed for lung cancer in patients with incipient SARS-CoV-2 permitted to appreciate early histologic findings of COVID-19 with hyperplastic pneumocytes with/without fibrin exudate, alveolar macrophages/myeloid cells, perivascular T-lymphocytic infiltrate and lack of hyaline membrane. While the COVID-19 pandemic has declined the rate of lung cancer diagnosis worldwide, some institutions have significantly limited detrimental effects. Histology related to early SARS-CoV-2 infection in surgical samples for lung cancer revealed specific histologic changes.

Indexed as

COVID-19Lung NeoplasmsEarly Detection of CancerHumansPandemicsSARS-CoV-2COVID-19epidemiologylung cancerpathologySARS-CoV-2

Identifiers

PMID38054903
PMCPMC10699334
OpenAlexW4389378863

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.