Evidence map›Paper›PMID 38054714›Full record

ArticleMicrobiology spectrum2024

Genome-wide screen reveals cellular functions that counteract rifampicin lethality in

Yu Wang, Han Fu, Xiao-Jie Shi, Guo-Ping Zhao, Liang-Dong Lyu

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Phenotypical-genetic virulence and resistance in atypical avian pathogenic Escherichia coli.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yu Wang *Key Laboratory of Medical Molecular Virology of the Ministry of Education/National Health Commission, School of Basic Medical Sciences and Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University , Shanghai, China.
Han Fu *Key Laboratory of Medical Molecular Virology of the Ministry of Education/National Health Commission, School of Basic Medical Sciences and Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University , Shanghai, China.
Xiao-Jie ShiKey Laboratory of Medical Molecular Virology of the Ministry of Education/National Health Commission, School of Basic Medical Sciences and Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University , Shanghai, China.
Guo-Ping ZhaoKey Laboratory of Medical Molecular Virology of the Ministry of Education/National Health Commission, School of Basic Medical Sciences and Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University , Shanghai, China.ORCID 0000-0002-7621-6620
Liang-Dong LyuKey Laboratory of Medical Molecular Virology of the Ministry of Education/National Health Commission, School of Basic Medical Sciences and Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University , Shanghai, China.ORCID 0000-0001-6391-6030
Fudan University · CNChinese Academy of Sciences · CN

Funding

MOST | National Natural Science Foundation of China (NSFC) 31830002MOST | National Natural Science Foundation of China (NSFC) 31970032MOST | National Natural Science Foundation of China (NSFC) 81991532The Science and Technology Commission of Shanghai Municipality ZD2021CY001
6 · The paper itself

Abstract

importanceRifamycins are a group of antibiotics with a wide antibacterial spectrum. Although the binding target of rifamycin has been well characterized, the mechanisms underlying the discrepant killing efficacy between gram-negative and gram-positive bacteria remain poorly understood. Using a high-throughput screen combined with targeted gene knockouts in the gram-negative model organism

Indexed as

RifampinRifamycinsAnti-Bacterial AgentsEscherichia coliMicrobial Sensitivity TestsAnti-Bacterial AgentsRifampinRifamycinsantibiotic susceptibilitydrug resistancerifamycinsTn-Seq

Identifiers

PMID38054714
PMCPMC10782999
OpenAlexW4389381207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.