Evidence map›Paper›PMID 38054713›Full record

ArticleMicrobiology spectrum2024

Construction of an arrayed CRISPRi library as a resource for essential gene function studies in

Jackson St Pierre, Justin Roberts, Mohammad A Alam, Robert C Shields

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jackson St PierreDepartment of Biological Sciences, Arkansas State University , Jonesboro, Arkansas, USA.
Justin RobertsDepartment of Chemistry & Physics, Arkansas State University , Jonesboro, Arkansas, USA.
Mohammad A AlamDepartment of Chemistry & Physics, Arkansas State University , Jonesboro, Arkansas, USA.ORCID 0000-0003-0258-3732
Robert C ShieldsDepartment of Biological Sciences, Arkansas State University , Jonesboro, Arkansas, USA.ORCID 0000-0002-8823-9504
Arkansas State University · US

Funding

Understanding Hesitant AdoptersP20GM103429 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Lawrence E Cornett, JERRY WARE · 2012 to 2026
$60.9M
Exploring Integrative Conjugative Elements in the Biology and Ecology of Oral StreptococciR03DE029882 · NIDCR · ARKANSAS STATE UNIVERSITY · PI SHIELDS, ROBERT COLQUHOUN · 2021 to 2022
$270k
NIDCR NIH HHS R03 DE029882NIGMS NIH HHS P20 GM103429
6 · The paper itself

Abstract

importanceThe construction of arrayed mutant libraries has advanced the field of bacterial genetics by allowing researchers to more efficiently study the exact function and importance of encoded genes. In this study, we constructed an arrayed clustered regularly interspaced short palindromic repeats interference (CRISPRi) library, known as

Indexed as

Genes, EssentialStreptococcus mutansClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsGene Libraryarrayed mutant libraryCRISPRiessential genesfunctional genomicsStreptococcus mutans

Identifiers

PMID38054713
PMCPMC10783072
OpenAlexW4389381203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.