Evidence map›Paper›PMID 38054654›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

An Erythrocyte-Templated Iron Single-Atom Nanozyme for Wound Healing.

Xiaonan Wang, Ting Liu, Mengxia Chen, Qian Liang, Jing Jiang, Lei Chen, Kelong Fan, Jinhua Zhang, Lizeng Gao

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. External Stimuli-Activable Single-Atom Nanozymes for Bioapplications.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Recent Advances in Nanozymes Toward Diabetic Foot Ulcers.International journal of nanomedicine · 2026
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Comprehensive wound healing using ETN@FeJournal of nanobiotechnology · 2025
    Article
  17. Article
  18. Ultrafast synthesis of L-His-FeFrontiers in bioengineering and biotechnology · 2025
    Article
  19. Article
  20. An Erythrocyte-Templated Iron Single-Atom Nanozyme for Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Xiaonan WangCAS Engineering Laboratory for Nanozyme, Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang, Beijing, 100101, China.
Ting LiuCollege of Life Science and Bioengineering, Beijing Jiaotong University, Haidian, Beijing, 100044, China.
Mengxia ChenCollege of Life Science and Bioengineering, Beijing Jiaotong University, Haidian, Beijing, 100044, China.
Qian LiangCAS Engineering Laboratory for Nanozyme, Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang, Beijing, 100101, China.
Jing JiangCAS Engineering Laboratory for Nanozyme, Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang, Beijing, 100101, China.
Lei ChenCAS Engineering Laboratory for Nanozyme, Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang, Beijing, 100101, China.
Kelong FanCAS Engineering Laboratory for Nanozyme, Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang, Beijing, 100101, China.
Jinhua ZhangCollege of Life Science and Bioengineering, Beijing Jiaotong University, Haidian, Beijing, 100044, China.
Lizeng GaoCAS Engineering Laboratory for Nanozyme, Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang, Beijing, 100101, China.ORCID 0000-0003-0265-4027
Chinese Academy of Sciences · CNBeijing Jiaotong University · CNJilin Normal University · CNJinan University · CN

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 22121003National Key Research and Development Program of China 2019YFA0709200National Natural Science Foundation of China 81930050National Natural Science Foundation of China U23A20686
6 · The paper itself

Abstract

Iron single-atom nanozymes represent a promising artificial enzyme with superior activity owing to uniform active sites that can precisely mimic active center of nature enzymes. However, current synthetic strategies are hard to guarantee each active site at single-atom state. In this work, an erythrocyte-templated strategy by utilizing intrinsic hemin active center of hemoglobin as sing-atom source for nanozyme formation is developed. By combining cell fixation, porous salinization, and high-temperature carbonization, erythrocytes are successfully served as uniform templates to synthesize nanozymes with fully single-atom FeN

Indexed as

HeminMethicillin-Resistant Staphylococcus aureusAnimalsErythrocytesIronMiceWound HealingHeminIronantibacterialerythrocytesiron single-atomnanozymeperoxidase-like activitywound healing

Identifiers

PMID38054654
PMCPMC10853745
OpenAlexW4389385785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.