Evidence map›Paper›PMID 38054423›Full record

ArticleInhalation toxicology2023

Vaping product exposure system (VaPES): a novel

Kevin D Schichlein, Charlotte A Love, Maxwell P Conolly, John L Kurz, Elise D Hickman, Phillip W Clapp, Ilona Jaspers

Abstract read
In one paragraph

Article in Inhalation toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kevin D SchichleinCurriculum in Toxicology & Environmental Medicine, University of NC at Chapel Hill, Chapel Hill, NC, USA.
Charlotte A LoveCurriculum in Toxicology & Environmental Medicine, University of NC at Chapel Hill, Chapel Hill, NC, USA.
Maxwell P ConollyCenter for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
John L KurzCenter for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Elise D HickmanCurriculum in Toxicology & Environmental Medicine, University of NC at Chapel Hill, Chapel Hill, NC, USA.
Phillip W ClappCurriculum in Toxicology & Environmental Medicine, University of NC at Chapel Hill, Chapel Hill, NC, USA.
Ilona JaspersCurriculum in Toxicology & Environmental Medicine, University of NC at Chapel Hill, Chapel Hill, NC, USA.

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
TOXICOLOGYT32ES007126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ILONA JASPERS, Bernard E. Weissman · 1985 to 2026
$13.0M
E-cig flavors and their effects on respiratory innate immune responsesR01HL139369 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JASPERS, ILONA · 2017 to 2020
$2.4M
Respiratory health effects of aerosolized delta-8-THC and its oxidation productsF31HL170762 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LOVE, CHARLOTTE ANN · 2023 to 2024
$79k
NHLBI NIH HHS F31 HL170762NHLBI NIH HHS R01 HL139369NIEHS NIH HHS P30 ES010126NIEHS NIH HHS T32 ES007126
6 · The paper itself

Abstract

objectiveDue to recent increases in the use of vaping devices, there is a high demand for research addressing the respiratory health effects of vaping products. Given the constantly changing nature of the vaping market with new devices, flavors, metals, and other chemicals rapidly emerging, there is a need for inexpensive and highly adaptable vaping device exposure systems. Here, we describe the design and validation of a novel MATERIALS AND

methodsWe developed an inexpensive, open-source

resultsThe Vaping Product Exposure System (VaPES) produced sufficient and uniform deposition for dose-response studies and was precise enough to observe biological responses to vaping exposures. VaPES was adapted to work with both pod and cartridge-based vaping devices.

conclusionWe have designed and validated a novel vaping device exposure system that will eliminate the need to use high-cost commercial exposure systems, lowering the barrier to entry of physiologically relevant vaping studies.

Indexed as

Electronic Nicotine Delivery SystemsVapingAerosolsHumansMetalsAerosolsMetalsaerosolcannabinoidscomputer-controllede-cigaretteexposureexposure systeminhalationin-vitroVaping

Identifiers

PMID38054423
PMCPMC10788097

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.