Evidence map›Paper›PMID 38054052›Full record

ArticleJCPP advances2023

Three year outcomes in infants with a family history of autism and/or attention deficit hyperactivity disorder.

Tony Charman, Greg Pasco, Alexandra Hendry, Tessel Bazelmans, Nisha Narvekar, Amy Goodwin, Hanna Halkola, Mary Agyapong, Rebecca Holman, Jannath Begum Ali and 5 more

Open access · goldAbstract read
In one paragraph

Article in JCPP advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

  1. Identification of Early Temperament Profiles in Infants at Elevated Likelihood for Autism and Attention-Deficit/Hyperactivity Disorder.Clinical psychological science : a journal of the Association for Psychological Science · 2026
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  3. Patterns of Early Development in Children with ADHD.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Tony CharmanInstitute of Psychiatry, Psychology & Neuroscience King's College London London UK.ORCID https://orcid.org/0000-0003-1993-6549
Greg PascoInstitute of Psychiatry, Psychology & Neuroscience King's College London London UK.
Alexandra HendryDepartment of Experimental Psychology University of Oxford Oxford UK.
Tessel BazelmansInstitute of Psychiatry, Psychology & Neuroscience King's College London London UK.
Nisha NarvekarInstitute of Psychiatry, Psychology & Neuroscience King's College London London UK.ORCID https://orcid.org/0000-0002-2196-4496
Amy GoodwinInstitute of Psychiatry, Psychology & Neuroscience King's College London London UK.
Hanna HalkolaInstitute of Psychiatry, Psychology & Neuroscience King's College London London UK.
Mary AgyapongInstitute of Psychiatry, Psychology & Neuroscience King's College London London UK.
Rebecca HolmanCentre for Brain and Cognitive Development Birkbeck University of London London UK.
Jannath Begum AliCentre for Brain and Cognitive Development Birkbeck University of London London UK.
Mutluhan ErsoyDepartment of Psychology Kastamonu University Kastamonu Turkey.
Mark H JohnsonCentre for Brain and Cognitive Development Birkbeck University of London London UK.
Andrew PicklesInstitute of Psychiatry, Psychology & Neuroscience King's College London London UK.
Emily J H JonesCentre for Brain and Cognitive Development Birkbeck University of London London UK.
STAARS Team
King's College London · GBBirkbeck, University of London · GBKastamonu University · TRUniversity of Cambridge · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Most research on early outcomes in infants with a family history (FH) of autism has focussed on categorically defined autism, although some have language and developmental delays. Less is known about outcomes in infants with a FH of attention deficit hyperactivity disorder (ADHD). Methods: Infants with and without a FH of autism and/or ADHD, due to a first-degree relative with either or both conditions, were recruited at 5 or 10 months. Three year outcomes were characterised using latent profile analysis (LPA) across measures of cognitive ability, adaptive functioning and autism, ADHD and anxiety traits ( Results: A Low Developmental Level + High Behavioural Concerns class had elevated autism, ADHD and anxiety scores, low cognitive and adaptive function, and included all but one child with autism. A Low Developmental Level + Typical Behaviour class had average cognitive ability and typical behaviour but low adaptive function. A Typical Developmental Level + Some Behavioural Concerns class had average cognitive and adaptive function but slightly elevated behaviour scores. A High Developmental Level + Typical Behaviour class had above average cognitive ability and typical behaviour. All four LPAs identified classes characterised by combinations of either, or both, Low Development Level and elevated behaviour scores, as well as a typically developing class. No classes had elevated autism or ADHD traits in isolation. Conclusions: Some infants with a FH of autism or ADHD have atypical developmental and behavioural outcomes, but do not show strong autism or ADHD traits in isolation. The field needs to recalibrate aims and methods to embrace the broader transdiagnostic pattern of outcomes seen in these infants.

Indexed as

ADHDautismearly childhoodinfancylatent profile analysis

Identifiers

PMID38054052
PMCPMC10694531
OpenAlexW4385482335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.