Evidence map›Paper›PMID 38053996›Full record

ArticleFrontiers in immunology2023

Epidermal keratinocyte-specific STAT3 deficiency aggravated atopic dermatitis-like skin inflammation in mice through TSLP upregulation.

Zhao-Yuan Wang, Yu-Xin Zheng, Fan Xu, Ying-Zhe Cui, Xue-Yan Chen, Si-Qi Chen, Bing-Xi Yan, Yuan Zhou, Min Zheng, Xiao-Yong Man

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

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  6. Integrative Assessment ofInternational journal of molecular sciences · 2025
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  9. International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zhao-Yuan Wang *Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yu-Xin Zheng *Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Fan XuDepartment of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ying-Zhe CuiDepartment of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xue-Yan ChenDepartment of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Si-Qi ChenDepartment of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Bing-Xi YanDepartment of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yuan ZhouDepartment of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Min ZhengDepartment of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiao-Yong ManDepartment of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Second Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is one of the most common inflammatory skin diseases with complex pathogenesis involving epidermal barrier dysfunction, skin microbiome abnormalities and type-2-skewed immune dysregulation. Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that plays critical roles in various biological processes. However, the role of STAT3 in epidermal keratinocytes in AD remains unclear. In this study, we generated an epidermal keratinocyte-specific

Indexed as

Dermatitis, AtopicAnimalsCytokinesDinitrochlorobenzeneInflammationKeratinocytesMiceSTAT3 Transcription FactorThymic Stromal LymphopoietinUp-RegulationCytokinesDinitrochlorobenzeneStat3 protein, mouseSTAT3 Transcription FactorThymic Stromal LymphopoietinTSLP protein, mouseatopic dermatitisDNCBkeratinocytesstat3TSLP

Identifiers

PMID38053996
PMCPMC10694200
OpenAlexW4388832935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.