Evidence map›Paper›PMID 38053838›Full record

ArticleFrontiers in pharmacology2023

Increased sinusoidal export of drug glucuronides is a compensative mechanism in liver cirrhosis of mice.

Rebekka Fendt, Ahmed Ghallab, Maiju Myllys, Ute Hofmann, Reham Hassan, Zaynab Hobloss, Daniela González, Lisa Brackhagen, Rosemarie Marchan, Karolina Edlund and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Rebekka Fendt *Institute for Systems Medicine with Focus on Organ Interaction, University Hospital RWTH Aachen, Aachen, Germany.
Ahmed Ghallab *Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Dortmund, Germany.
Maiju MyllysLeibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Dortmund, Germany.
Ute HofmannDr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University of Tübingen, Stuttgart, Germany.
Reham HassanLeibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Dortmund, Germany.
Zaynab HoblossLeibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Dortmund, Germany.
Daniela GonzálezLeibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Dortmund, Germany.
Lisa BrackhagenLeibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Dortmund, Germany.
Rosemarie MarchanLeibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Dortmund, Germany.
Karolina EdlundLeibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Dortmund, Germany.
Abdel-Latif SeddekDepartment of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt.
Noha AbdelmageedDepartment of Pharmacology, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt.
Lars M BlankInstitute of Applied Microbiology-iAMB, Aachen Biology and Biotechnology-ABBt, RWTH Aachen University, Aachen, Germany.
Jan-Frederik SchlenderPharmacometrics, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
Christian H HollandLeibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Dortmund, Germany.
Jan G HengstlerLeibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Dortmund, Germany.
Lars KuepferInstitute for Systems Medicine with Focus on Organ Interaction, University Hospital RWTH Aachen, Aachen, Germany.
TU Dortmund University · DERWTH Aachen University · DESouth Valley University · EGBayer (Germany) · DEDr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology · DESohag University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

drug cocktaildrug metabolismglucuronidesliver cirrhosisPBPKsinusoidal transportsystems medicinesystems pharmacology

Identifiers

PMID38053838
PMCPMC10694292
OpenAlexW4388830082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.