Evidence map›Paper›PMID 38053830›Full record

ArticleNutrition research and practice2023

Aqueous extract of

Jae In Jung, Yean-Jung Choi, Jinhak Kim, Kwang-Soo Baek, Eun Ji Kim

Open access · diamondAbstract read
In one paragraph

Article in Nutrition research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. A Triterpenoid-Enriched GLE70 Fraction FromFood science & nutrition · 2026
    Article
  2. Hepatoprotective Effect ofInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jae In JungIndustry coupled Cooperation Center for Bio Healthcare Materials, Hallym University, Chuncheon 24252, Korea.ORCID https://orcid.org/0000-0002-4475-1434
Yean-Jung ChoiDepartment of Food and Nutrition, Sahmyook University, Seoul 01795, Korea.ORCID https://orcid.org/0000-0002-4613-2098
Jinhak KimR&D Division, Daehan Chemtech Co. Ltd., Gwacheon 13840, Korea.ORCID https://orcid.org/0000-0002-7329-4324
Kwang-Soo BaekR&D Division, Daehan Chemtech Co. Ltd., Gwacheon 13840, Korea.ORCID https://orcid.org/0000-0003-3164-7379
Eun Ji KimIndustry coupled Cooperation Center for Bio Healthcare Materials, Hallym University, Chuncheon 24252, Korea.ORCID https://orcid.org/0000-0001-9305-4769
Dae Hwa Pharm (South Korea) · KRHallym University · KRSahmyook University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesExcessive alcohol consumption has harmful health effects, including alcohol hangovers and alcohol-related liver disease. Therefore, methods to accelerate the alcohol metabolism are needed. MATERIALS/

methodsLN was administered orally to SD rats 1 h before ethanol administration (3 g/kg body weight [BW]) at 100 and 300 mg/kg BW. Blood samples were collected 0.5, 1, 2, and 4 h after ethanol administration. The livers were excised 1 h after ethanol administration to determine the hepatic enzyme activity. The alcohol dehydrogenase (ADH), aldehyde dehydrogenase (ALDH), superoxide dismutase (SOD), and glutathione peroxidase (GPx) activities in the liver tissue were measured.

resultsLN decreased the serum ethanol and acetaldehyde levels in ethanol-administered rats. LN increased the hepatic ADH and ALDH activities but decreased the alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase activities in the ethanol-administered rats. In addition, LN inhibited lipid peroxidation and increased the activities of SOD and GPx.

conclusionsLN modulates the mediators of various etiological effects of excessive alcohol consumption and enhances the alcohol metabolism and antioxidant activity, making it a potential candidate for hangover treatments.

Indexed as

alcohol dehydrogenasealdehyde dehydrogenaseglutathione peroxidaseLaurus nobilissuperoxide dismutase

Identifiers

PMID38053830
PMCPMC10694424
OpenAlexW4389148872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.