Evidence map›Paper›PMID 38053688›Full record

ArticleRSC advances2023

Five and six membered heterocyclic rings endowed with azobenzene as dual EGFR

Kurls E Anwer, Sanadelaslam S A El-Hddad, Nour E A Abd El-Sattar, Ahmed El-Morsy, Fathalla Khedr, Samy Mohamady, Doaa E Keshek, Samir A Salama, Khaled El-Adl, Noura S Hanafy

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Design, synthesis,RSC advances · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Dual VEGFR-2 and EGFRFuture medicinal chemistry · 2025
    Article
  12. Article
  13. Rationale,RSC advances · 2024
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 4 countries.

Kurls E AnwerDepartment of Chemistry, Faculty of Science, Ain Shams University Abbassia Cairo Egypt.
Sanadelaslam S A El-HddadPharmaceutical Chemistry Department, Faculty of Pharmacy, Omar Almukhtar University Libya.ORCID https://orcid.org/0000-0002-7183-6505
Nour E A Abd El-SattarDepartment of Chemistry, Faculty of Science, Ain Shams University Abbassia Cairo Egypt.ORCID https://orcid.org/0000-0001-6680-4448
Ahmed El-MorsyPharmaceutical Chemistry Department, College of Pharmacy, The Islamic University Najaf Iraq.
Fathalla KhedrPharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University Nasr City 11884 Cairo Egypt khaled.eladl@hu.edu.eg eladlkhaled74@azhar.edu.eg eladlkhaled74@yahoo.com.
Samy MohamadyPharmaceutical Chemistry Department, Faculty of Pharmacy, The British University in Egypt Cairo Egypt.
Doaa E KeshekDepartment of Biology, Jumum College University, Umm Al-Qura University P.O. Box 7388 Makkah 21955 Sudia Arabia.
Samir A SalamaDivision of Biochemistry, Department of Pharmacology, College of Pharmacy, Taif University P.O. Box 11099 Taif 21944 Kingdom of Saudi Arabia.
Khaled El-AdlPharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University Nasr City 11884 Cairo Egypt khaled.eladl@hu.edu.eg eladlkhaled74@azhar.edu.eg eladlkhaled74@yahoo.com.ORCID https://orcid.org/0000-0002-8922-9770
Noura S HanafyPharmaceutical Chemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development Cairo Egypt.
Ain Shams University · EGAl-Azhar University · EGBritish University in Egypt · EGHeliopolis University · EGIraqi University · IQOmar Al-Mukhtar University · LYTaif University · SAUmm al-Qura University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel azobenzene scaffold-joined heterocyclic isoxazole, pyrazole, triazole, and/or triazine moieties have been developed and synthesized utilizing microwave and traditional methods. Our compounds were tested for growth inhibition of A549, MCF-7, HCT-116, and HepG2 tumors by dual targeting the VEGFR-2 and EGFR

Identifiers

PMID38053688
PMCPMC10695193
OpenAlexW4389318924

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.