Evidence map›Paper›PMID 38053574›Full record

ArticleMicrobial cell (Graz, Austria)2023

Extracellular DNA secreted in yeast cultures is metabolism-specific and inhibits cell proliferation.

Elisabetta de Alteriis, Guido Incerti, Fabrizio Cartenì, Maria Luisa Chiusano, Chiara Colantuono, Emanuela Palomba, Pasquale Termolino, Francesco Monticolo, Alfonso Esposito, Giuliano Bonanomi and 10 more

Abstract read
In one paragraph

Article in Microbial cell (Graz, Austria), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Epigenomes · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Self-DNA inMolecules (Basel, Switzerland) · 2024
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Elisabetta de AlteriisDepartment of Biology, University of Naples "Federico II", Via Cinthia 26, 80126 Naples, Italy.
Guido IncertiDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, via delle Scienze 206, 33100 Udine, Italy.
Fabrizio CartenìDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.
Maria Luisa ChiusanoDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.
Chiara ColantuonoDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.
Emanuela PalombaInstitute of Biosciences and Bioresources CNR, Via Università 133, 80055 Portici (NA), Italy.
Pasquale TermolinoInstitute of Biosciences and Bioresources CNR, Via Università 133, 80055 Portici (NA), Italy.
Francesco MonticoloDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.
Alfonso EspositoDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.
Giuliano BonanomiDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.
Rosanna CapparelliDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.
Marco IannacconeDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.
Alessandro FoscariDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, via delle Scienze 206, 33100 Udine, Italy.
Carmine LandiDepartment of Industrial Engineering, Università degli Studi di Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, SA, Italy.
Palma ParascandolaDepartment of Industrial Engineering, Università degli Studi di Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, SA, Italy.
Massimo SanchezIstituto Superiore di Sanità (ISS) Core Facilities, Viale Regina Elena 299, 00161 Rome, Italy.
Valentina TirelliIstituto Superiore di Sanità (ISS) Core Facilities, Viale Regina Elena 299, 00161 Rome, Italy.
Bruna de FalcoDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.
Virginia LanzottiDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.
Stefano MazzoleniDepartment of Agricultural Sciences, University of Naples "Federico II", via Università 100, 80055 Portici (NA), Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular DNA (exDNA) can be actively released by living cells and different putative functions have been attributed to it. Further, homologous exDNA has been reported to exert species-specific inhibitory effects on several organisms. Here, we demonstrate by different experimental evidence, including

Indexed as

1H NMRcell cycleeccDNAexDNAmetabolomicsself-DNA

Identifiers

PMID38053574
PMCPMC10695634

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.